Chronic histological outcomes of indirect traumatic optic neuropathy in adolescent mice: persistent degeneration and temporally regulated glial responses

SM Hetzer, EM Shalosky, JN Torrens, NK Evanson - Cells, 2021 - mdpi.com
Injury to the optic nerve, termed, traumatic optic neuropathy (TON) is a known comorbidity of
traumatic brain injury (TBI) and is now known to cause chronic and progressive retinal …

Traumatic optic neuropathy is associated with visual impairment, neurodegeneration, and endoplasmic reticulum stress in adolescent mice

SM Hetzer, F Guilhaume-Correa, D Day, A Bedolla… - Cells, 2021 - mdpi.com
Traumatic brain injury (TBI) results in a number of impairments, often including visual
symptoms. In some cases, visual impairments after head trauma are mediated by traumatic …

[HTML][HTML] A controlled impact of optic nerve as a new model of traumatic optic neuropathy in mouse

AS Ibrahim, K Elmasry, M Wan… - … & Visual Science, 2018 - jov.arvojournals.org
Purpose: Traumatic optic neuropathy (TON) is the most feared visual consequence of head
and ocular trauma in both military and civilian communities, for which standard treatment …

[HTML][HTML] Optic tract injury after closed head traumatic brain injury in mice: A model of indirect traumatic optic neuropathy

NK Evanson, F Guilhaume-Correa, JP Herman… - PLoS …, 2018 - journals.plos.org
Adult male C57BL/6J mice have previously been reported to have motor and memory
deficits after experimental closed head traumatic brain injury (TBI), without associated gross …

Traumatic brain injury-related optic nerve damage

J Qiu, M Boucher, G Conley, Y Li… - … of Neuropathology & …, 2022 - academic.oup.com
Vision disorders are associated with traumatic brain injury (TBI) in 20%–40% of clinical
cases and involve a diverse set of potential symptoms that can present acutely or …

Progression and pathology of traumatic optic neuropathy from repeated primary blast exposure

A Bernardo-Colón, V Vest, ML Cooper… - Frontiers in …, 2019 - frontiersin.org
Indirect traumatic optic neuropathy (ITON) is a condition that is often associated with
traumatic brain injury and can result in significant vision loss due to degeneration of retinal …

Repetitive mild traumatic brain injury causes optic nerve and retinal damage in a mouse model

R Tzekov, A Quezada, M Gautier… - … of Neuropathology & …, 2014 - academic.oup.com
There is increasing evidence that long-lasting morphologic and functional consequences
can be present in the human visual system after repetitive mild traumatic brain injury (r …

Connecting endoplasmic reticulum and oxidative stress to retinal degeneration, TBI, and traumatic optic neuropathy

SM Cansler, NK Evanson - Journal of neuroscience research, 2020 - Wiley Online Library
Traumatic optic neuropathy (TON) is commonly associated with head trauma, and thus is a
known comorbidity of traumatic brain injury (TBI). TON has not received much attention in …

RGC and vision loss from traumatic optic neuropathy induced by repetitive closed head trauma is dependent on timing and force of impact

RS Khan, AG Ross, P Aravand, K Dine… - … vision science & …, 2021 - tvst.arvojournals.org
Purpose: Traumatic optic neuropathy (TON) is often caused by blunt head trauma and has
no currently effective treatment. Common animal models of TON induced by surgical crush …

Diffuse traumatic axonal injury in the optic nerve does not elicit retinal ganglion cell loss

J Wang, MA Fox, JT Povlishock - Journal of Neuropathology & …, 2013 - academic.oup.com
Much of the morbidity after traumatic brain injury (TBI) is associated with traumatic axonal
injury (TAI). Although most TAI studies focus on corpus callosum white matter, the visual …