[HTML][HTML] Diagnostic accuracy of three commercially available one step RT-PCR assays for the detection of SARS-CoV-2 in resource limited settings

A Sisay, A Abera, B Dufera, T Endrias, G Tasew… - PloS one, 2022 - journals.plos.org
Background COVID-19 is an ongoing public health pandemic regardless of the countless
efforts made by various actors. Quality diagnostic tests are important for early detection and …

[HTML][HTML] Real-time PCR-based SARS-CoV-2 detection in Canadian laboratories

JJ LeBlanc, JB Gubbay, Y Li, R Needle… - Journal of Clinical …, 2020 - Elsevier
With emergence of pandemic COVID-19, rapid and accurate diagnostic testing is essential.
This study compared laboratory-developed tests (LDTs) used for the detection of SARS-CoV …

[HTML][HTML] COVID-19 rapid diagnostic test could contain transmission in low-and middle-income countries

A Olalekan, B Iwalokun, OM Akinloye… - African Journal of …, 2020 - scielo.org.za
OLALEKAN, Adesola et al. COVID-19 rapid diagnostic test could contain transmission in low-
and middle-income countries. Afr. J. Lab. Med.[online]. 2020, vol. 9, n. 1, pp. 1-8. ISSN 2225 …

Development and validation of RT-PCR assays for testing for SARS-CoV-2

K Pabbaraju, AA Wong, M Douesnard… - Official Journal of …, 2021 - jammi.utpjournals.press
Background: The recent emergence and rapid global spread of severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) demonstrates the urgent need for laboratory …

[HTML][HTML] Real-life clinical sensitivity of SARS-CoV-2 RT-PCR test in symptomatic patients

E Kortela, V Kirjavainen, MJ Ahava, ST Jokiranta… - PloS one, 2021 - journals.plos.org
Background Understanding the false negative rates of SARS-CoV-2 RT-PCR testing is
pivotal for the management of the COVID-19 pandemic and it has implications for patient …

[HTML][HTML] Analytical performance of COVID-19 detection methods (RT-PCR): scientific and societal concerns

R Verna, W Alallon, M Murakami, CPM Hayward… - Life, 2021 - mdpi.com
Background. Health and social management of the SARS-CoV-2 epidemic, responsible for
the COVID-19 disease, requires both screening tools and diagnostic procedures. Reliable …

[HTML][HTML] Clinical validation of a rapid variant-proof RT-RPA assay for the detection of SARS-CoV-2

D Cherkaoui, J Heaney, D Huang, M Byott, BS Miller… - Diagnostics, 2022 - mdpi.com
The COVID-19 pandemic has unveiled a pressing need to expand the diagnostic landscape
to permit high-volume testing in peak demand. Rapid nucleic acid testing based on …

[PDF][PDF] External peer review of the RTPCR test to detect SARS-CoV-2 reveals 10 major scientific flaws at the molecular and methodological level: consequences for …

P Borger, BR Malhotra, M Yeadon, C Craig… - Preprint …, 2020 - howbadismybatch.com
In the publication entitled “Detection of 2019 novel coronavirus (2019-nCoV) by real-time RT-
PCR”(Eurosurveillance 25 (8) 2020) the authors present a diagnostic workflow and RT …

[HTML][HTML] Clinical evaluation of a multiplex real-time RT-PCR assay for detection of SARS-CoV-2 in individual and pooled upper respiratory tract samples

M Laverack, RL Tallmadge, R Venugopalan, B Cronk… - Archives of …, 2021 - Springer
The aim of this study was to identify and validate a sensitive, high-throughput, and cost-
effective SARS-CoV-2 real-time RT-PCR assay to be used as a surveillance and diagnostic …

Analysis of external quality assessment samples revealed crucial performance differences between commercial RT-PCR assays for SARS-CoV-2 detection when …

M Malecki, J Luesebrink, AF Wendel… - Journal of Virological …, 2021 - Elsevier
In limelight of the ongoing pandemic SARS-CoV-2 testing is critical for the diagnosis of
infected patients, contact-tracing and mitigating the transmission. Diagnostic laboratories are …