GLP-1 and GIP receptor agonists in the treatment of Parkinson's disease: Translational systematic review and meta-analysis protocol of clinical and preclinical studies
C Vaccari, D Grotto, TV Pereira, JLV de Camargo… - PloS one, 2021 - journals.plos.org
Background Parkinson's disease (PD) is a progressive multifactorial neurodegenerative
condition. Epidemiological studies have shown that patients with type 2 diabetes mellitus …
condition. Epidemiological studies have shown that patients with type 2 diabetes mellitus …
GLP-1 receptor agonists: a New Treatment in Parkinson's Disease
K Kalinderi, V Papaliagkas, L Fidani - International Journal of Molecular …, 2024 - mdpi.com
Parkinson's disease (PD) is one of the most common neurodegenerative diseases. Recent
data highlight similarities between neurodegenerative diseases, including PD and type 2 …
data highlight similarities between neurodegenerative diseases, including PD and type 2 …
Glucagon-like peptide-1 (GLP-1)-based receptor agonists as a treatment for Parkinson's disease
Introduction Accumulating evidence supports the evaluation of glucagon-like peptide-1 (GLP-
1) receptor (R) agonists for the treatment of the underlying pathology causing Parkinson's …
1) receptor (R) agonists for the treatment of the underlying pathology causing Parkinson's …
[HTML][HTML] Clinical Trial Highlights–GLP-1 agonists
K McFarthing, D Larson, T Simuni - Journal of Parkinson's disease, 2020 - ncbi.nlm.nih.gov
Parkinson's Disease (PD) is a heterogeneous, long-term neurodegenerative condition, for
which there are no therapies proven to slow or stop progression. At the same time …
which there are no therapies proven to slow or stop progression. At the same time …
Therapeutic application of GLP-1 and GIP receptor agonists in Parkinson's disease
X Yang, P Feng, R Ji, Y Ren, W Wei… - Expert opinion on …, 2022 - Taylor & Francis
Introduction Diabetes is a risk factor for Parkinson's disease (PD) and shares similar
dysregulated insulin pathways. Glucagon-like peptide-1 (GLP-1) analogs originally …
dysregulated insulin pathways. Glucagon-like peptide-1 (GLP-1) analogs originally …
Repurposing GLP-1 receptor agonists for Parkinson's disease: current evidence and future opportunities
DB Victorino, M Nejm, M Guimarães-Marques… - Pharmaceutical …, 2021 - Springer
The global burden of chronic disorders such as Parkinson's disease (PD) has rapidly
increased over recent decades. Despite an increasing understanding of PD …
increased over recent decades. Despite an increasing understanding of PD …
GLP‐1 receptor agonists for Parkinson's disease
CA Mulvaney, GS Duarte, J Handley… - Cochrane Database …, 2020 - cochranelibrary.com
Background Parkinson's disease (PD) is a progressive disorder characterised by both motor
and non‐motor problems. Glucagon‐like peptide‐1 (GLP‐1) receptor agonists, licensed for …
and non‐motor problems. Glucagon‐like peptide‐1 (GLP‐1) receptor agonists, licensed for …
[HTML][HTML] Glucagon-like peptide-1 class drugs show clear protective effects in Parkinson's and Alzheimer's disease clinical trials: A revolution in the making?
C Hölscher - Neuropharmacology, 2024 - Elsevier
Parkinson's disease (PD) is a complex syndrome for which there is no disease-modifying
treatment on the market. However, a group of drugs from the Glucagon-like peptide-1 (GLP …
treatment on the market. However, a group of drugs from the Glucagon-like peptide-1 (GLP …
[HTML][HTML] The glucagon-like peptide 1 (GLP) receptor as a therapeutic target in Parkinson's disease: mechanisms of action
D Athauda, T Foltynie - Drug discovery today, 2016 - Elsevier
Highlights•GLP-1 analogs can cross the blood–brain barrier and stimulate the GLP-1
receptor in the brain.•Stimulation of the GLP-1 receptor has shown effects on mitochondrial …
receptor in the brain.•Stimulation of the GLP-1 receptor has shown effects on mitochondrial …
GLP-1a: going beyond traditional use
LF Laurindo, SM Barbalho, EL Guiguer… - International Journal of …, 2022 - mdpi.com
Glucagon-like peptide-1 (GLP-1) is a human incretin hormone derived from the proglucagon
molecule. GLP-1 receptor agonists are frequently used to treat type 2 diabetes mellitus and …
molecule. GLP-1 receptor agonists are frequently used to treat type 2 diabetes mellitus and …