Background: Asthma is complex disease which pathogenesis is a mix of environmental and
genetic factors. A predisposition of airways to bronchoconstriction is one of main risk factors …

Abstract Introduction Beta‐2‐adrenergic receptor (ADRB2) is present in the cells of the
respiratory tract, including bronchial smooth muscle cells and bronchial epithelium, and is a …

Background: Beta 2-adrenergic receptor is expressed in airway smooth muscle and induces
bronchial relaxation. It is assumed that two common investigated polymorphisms of the …

BACKGROUND: The association between genetic polymorphisms of ADRβ2, IL-4, and
ADAM3 and asthma remains undetermined. Furthermore, it is not clear as to whether these …

ADAM33 is the first reported asthma-susceptible gene identified by positional cloning.
ADAM33 is located on chromosome 20p13 and codes for a protein important for cell fusion …

Background The gene encoding a disintegrin and metalloproteinase domain 33 (ADAM33)
is known to be associated with asthma in different ethnic groups. In Iraq, among the Arab …

Objective: To investigate the association between rs1042713 polymorphisms of ADRB2
gene and the susceptibility of asthma in Chinese Population by meta-analysis. Methods: The …

Background: The β2-adrenergic receptor (ADRB2) is the most common adrenergic receptor
in the lung, and associations between ADRB2 polymorphisms and intermediate phenotypes …

There is strong evidence on the interaction of several genetic variations and environmental
conditions in the etiology of asthma. Association of a disintegrin and metalloproteinase 33 …

Major progress has been made during the past few years in developing a better
understanding of the genetic basis of asthma, which has led to the identification of several …