In the past few years, it has been made increasingly evident that nitric oxide (NO), a simple
gas with free radical chemical properties, plays a very important role in the pathology of the …

Publisher Summary A variety of mechanisms have been proposed for NO neurotoxicity,
including inhibition of mitochondrial enzymes such as cis-aconitase, inhibition of the …

Nitric oxide (NO) is a molecule with pleiotropic effects in different tissues. NO is synthesized
by NO synthases (NOS), a family with four major types: endothelial, neuronal, inducible and …

NO has clearly revolutionized our thinking about aspects of neurotransmission and neuronal
signaling. NO is emerging as an important regulator of a variety of physiologic processes; …

Nitric oxide (NO) has only recently been appreciated as a normal biologic substance with a
role in signal transduction. It was first identified as endothelial-derived relaxing factor in …

Publisher Summary Nitric Oxide (NO) has clearly revolutionized research about aspects of
neurotransmission and neuronal signaling. It has also radically altered studies about how …

Whether nitric oxide is cytodestructive or cytoprotective is of obvious clinical importance. The
debate on this subject in the past decade has generated much “heat and light”. This paper …

Nitric oxide (NO) has revolutionized our conceptions about neurotransmission. NO is not
stored in synaptic vesicles, is not released by exocytosis, and does not mediate its action by …

The important role played by nitric oxide (NO) in the central nervous system has largely
been emphasized in the recent literature. It can originate at least from four different sources …

Nitric oxide (NO) is a unique biological messenger molecule which mediates diverse
physiologic roles. NO mediates blood vessel relaxation by endothelium, immune activity of …