De Novo Acute Myeloid Leukemia with Combined CBFB-MYH11 and BCR-ABL1 Gene Rearrangements: A Case Report and Review of Literature

VR Sethapati, R Jabr, L Shune… - Case Reports in …, 2020 - Wiley Online Library
Acute myeloid leukemia (AML) with inv (16)(p13. 1q22) resulting in CBFB-MYH11 fusion is
associated with a favorable prognosis. The presence of a KIT mutation modifies it to an …

Detection of a novel CBFB-MYH11 fusion transcript in acute myeloid leukemia M1 with inv (16)(p13q22)

K Kurata, K Yamamoto, Y Okazaki, Y Noguchi, K Matsui… - Cancer Genetics, 2020 - Elsevier
Acute myeloid leukemia (AML) with an inv (16)(p13q22) or t (16; 16)(p13; q22) chromosomal
abnormality represents one of the most common subtypes of de novo cases. These …

De novo acute myeloid leukemia with Philadelphia chromosome (BCR–ABL) and inversion 16 (CBFB–MYH11): report of two cases and review of the literature

CG Roth, L Contis, S Gupta, M Agha… - Leukemia & …, 2011 - Taylor & Francis
Cytogenetic and molecular studies play a major role in myeloid disease subclassification
and risk stratification. The 2008 World Health Organization (WHO) classification [1] …

[HTML][HTML] A novel cryptic CBFB-MYH11 gene fusion present at birth leading to acute myeloid leukemia and allowing molecular monitoring for minimal residual disease

PJ Poddighe, MA Veening, MB Mansur… - Human Pathology: Case …, 2018 - Elsevier
Acute myeloid leukemia (AML) with the inv (16)/t (16; 16) karyotype is associated with a
favourable prognosis, showing longer periods of complete remission and high overall …

inv(16)/t(16;16) acute myeloid leukemia with non–type A CBFB-MYH11 fusions associate with distinct clinical and genetic features and lack KIT mutations

S Schwind, CG Edwards, D Nicolet… - Blood, The Journal …, 2013 - ashpublications.org
Abstract The inv (16)(p13q22)/t (16; 16)(p13; q22) in acute myeloid leukemia results in
multiple CBFB-MYH11 fusion transcripts, with type A being most frequent. The biologic and …

Myeloid neoplasms with concurrent BCR‐ABL1 and CBFB rearrangements: A series of 10 cases of a clinically aggressive neoplasm

A Salem, S Loghavi, G Tang, YO Huh… - American journal of …, 2017 - Wiley Online Library
Chronic myeloid leukemia (CML) is defined by the presence of t (9; 22)(q34; q11. 2)/BCR‐
ABL1. Additional chromosomal abnormalities confer an adverse prognosis and are …

Acute myeloid leukemia with t (16; 16)(p13; q22) showing a new CBFB-MYH11 fusion transcript associated with an atypical leukemic blasts morphology

F Albano, L Anelli, A Zagaria, N Coccaro, G Tota… - Human pathology, 2014 - Elsevier
Acute myeloid leukemia (AML) cases with inv (16)(p13q22) or t (16; 16)(p13; q22) are
characterized by multiple CBFB-MYH11 fusion transcripts, type A being the most frequent …

Clinical analysis of acute myeloid leukemia with CBFB-MYH11-positive

TT Cao, MH Zhou, L Yuan, Q Wang, LP Dou… - … shi yan xue ye xue za …, 2013 - europepmc.org
The study was aimed to investigate the clinical characteristics of acute myeloid leukemia
(AML) with CBFB-MYH11 gene. The clinical data of 12 cases were analyzed retrospectively …

Rapid identification of CBFB-MYH11–positive acute myeloid leukemia (AML) cases by one single MYH11 real-time RT-PCR

BA van der Reijden, M Massop, E Tönnissen… - Blood, 2003 - ashpublications.org
The inv (16)(p13q22) rearrangement is present in approximately 10% of cases with de novo
acute myeloid leukemia (AML) and results in a CBFB-MYH11 gene fusion. 1 Patients with …

Acute myeloid leukemia with inv (16) with CBFB–MYH11, 3′ CBFB deletion, variant t (9; 22) with BCR–ABL1, and del (7)(q22q32) in a pediatric patient: case report …

CA Tirado, F Valdez, L Klesse, NJ Karandikar… - Cancer genetics and …, 2010 - Elsevier
Coexistence of inv (16) and t (9; 22) is a rare chromosomal aberration, one that has been
described in chronic myelogenous leukemia (CML), mainly in myeloid blast crisis, and de …