Nanoscale lipid vesicles are attractive vehicles for drug delivery. Although often considered
as soft nanoparticles in terms of mechanical deformability, the fluidic nature of the lipid …

Cholesterol plays a critical role in modulating the lipid membrane properties of biological
and biomimetic systems and recent attention has focused on its role in the functions of sub …

The size of membrane-enveloped virus particles, exosomes, and lipid vesicles strongly
impacts functional properties in biological and applied contexts. Multivalent ligand–receptor …

While cells offer numerous inspiring examples in which membrane morphology and function
are controlled by interactions with viruses or proteins, we still lack design principles for …

The efficiency of lipid nanoparticle uptake across cellular membranes is strongly dependent
on the very first interaction step. Detailed understanding of this step is in part hampered by …

Cholesterol is a major component of many lipid-based drug delivery systems, including
cationic lipid nanoparticles. Despite its critical role in the drug release stage, the underlying …

Due to different interactions between lipids and proteins, a plasma membrane can
segregate into different membrane domains. Among them, ordered functional membrane …

Lipid nanoparticles (LNPs) are a leading biomimetic drug delivery platform due to their
distinctive advantages and highly tunable formulations. A mechanistic understanding of the …

The plasma membrane is a highly complex multicomponent system that is central to the
functioning of cells. Cholesterol, a key lipid component of the plasma membrane, promotes …

Liposomes composed of fatty acids and phospholipids are frequently used as model
systems for biological cell membranes. In many applications, the encapsulation of proteins …