Background Prior studies in bipolar disorders (BD) have suggested that oxidative stress and
cellular ageing play a key role in the pathophysiology of BD. Nevertheless, oxidative stress …

Excessive oxidative stress-generated nucleoside damage seems to play a key role in
bipolar disorder (BD) and may present a trait phenomenon associated with familial risk and …

Objectives Increased oxidative stress generated nucleoside damage seems to play a crucial
role in bipolar disorder (BD) pathophysiology. It may contribute to accelerated ageing and …

Objectives The pathophysiological mechanisms underlying bipolar disorder and its multi‐
system nature are unclear. Oxidatively generated damage to nucleosides has been …

The mechanisms underlying bipolar disorder (BD) and the associated medical burden are
unclear. Damage generated by oxidation of nucleosides may be implicated in BD …

OBJECTIVE: There is an emerging body of data suggesting that oxidative stress may be
associated with the pathophysiology of bipolar disorder (BD). In the present study we …

Objective Oxidative DNA damage has been associated with the pathophysiology of bipolar
disorder (BD) as one of the common pathways between increased medical comorbidity and …

Bipolar disorder (BD) is a mental disorder characterized by recurrent relapses of affective
episodes, cognitive impairment, illness progression, and reduced life expectancy. Increased …

Enhanced oxidative stress-generated nucleoside damage may contribute to the increased
cardiovascular disease mortality in patients with bipolar disorder (BD) but the association …

Previous evidence suggests elevated levels of oxidatively-induced DNA damage,
particularly 8-hydroxy-2'-deoxyguanosine (8-OH-dG), and abnormalities in the repair of 8 …