Smart cargo delivery system based on mesoporous nanoparticles for bone disease diagnosis and treatment

P Pan, Q Yue, J Li, M Gao, X Yang, Y Ren… - Advanced …, 2021 - Wiley Online Library
Bone diseases constitute a major issue for modern societies as a consequence of
progressive aging. Advantages such as open mesoporous channel, high specific surface …

Microenvironment-responsive nanocarriers for targeted bone disease therapy

M Li, B Yu, S Wang, F Zhou, J Cui, J Su - Nano Today, 2023 - Elsevier
Nanomedicines with controlled drug release have received increasing attention as an
advanced therapeutic strategy for bone diseases. To traverse biological barriers towards …

Mesoporous silica nanoparticles for tissue‐engineering applications

L Chen, X Zhou, C He - Wiley Interdisciplinary Reviews …, 2019 - Wiley Online Library
Mesoporous silica nanoparticles (MSNs) have been widely investigated as a nanocarrier for
the delivery of various cargoes in nanomedicine. The application of MSNs in tissue …

[HTML][HTML] Advances in porous inorganic nanomaterials for bone regeneration

H Dai, S Hosseinpour, S Hua, C Xu - Nano TransMed, 2022 - Elsevier
Porous inorganic materials such as mesoporous silica nanoparticles (MSNs), mesoporous
bioactive glasses (MBGs), porous calcium phosphates, and metal-organic frameworks …

A novel vertical aligned mesoporous silica coated nanohydroxyapatite particle as efficient dexamethasone carrier for potential application in osteogenesis

S Jia, Y Liu, Z Ma, C Liu, J Chai, Z Li… - Biomedical …, 2021 - iopscience.iop.org
Bone defect is a common problem and inducing osteoblasts differentiation is the key
process for the regenerative repair. Recently, the mesoporous silica (MS) coated …

Microenvironment‐Responsive Targeted Nanomedicine for a Collaborative Integration of Tumor Theranostics and Bone Defect Repair

W Wang, W Kang, X Zhang, X Zheng… - Advanced …, 2024 - Wiley Online Library
Despite advancements in breast cancer treatment, bone metastases remain a significant
concern for patients with advanced breast cancer. Current theranostics strategies face …

Chemically engineered mesoporous silica nanoparticles-based intelligent delivery systems for theranostic applications in multiple cancerous/non-cancerous diseases

S Zhou, Q Zhong, Y Wang, P Hu, W Zhong… - Coordination Chemistry …, 2022 - Elsevier
In recent years, the unprecedented advances of biomedical nanotechnology have spurred
the development of drug delivery systems (DDSs) based on multifarious nanomaterials in …

Targeting bone microenvironments for treatment and early detection of cancer bone metastatic niches

H Yang, Z Yu, S Ji, Q Huo, J Yan, Y Gao, Y Niu… - Journal of Controlled …, 2022 - Elsevier
Bone tissues are the main metastatic sites of many cancers, and bone metastasis is an
important cause of death. When bone metastasis occurs, dynamic interactions between …

Hierarchically nanostructured mesoporous carbonated hydroxyapatite microspheres for drug delivery systems with high drug-loading capacity

T Long, YP Guo, YZ Liu, ZA Zhu - RSC advances, 2013 - pubs.rsc.org
Hierarchically nanostructured mesoporous carbonated hydroxyapatite microspheres have a
great potential for bone-implantable drug-delivery applications due to their large specific …

Mesoporous silica-based hybrid materials for bone-specific drug delivery

L Pasqua, IE De Napoli, M De Santo, M Greco… - Nanoscale …, 2019 - pubs.rsc.org
A mesoporous silica-based drug delivery device potentially useful for bone-specific drug
delivery has been designed, developed and characterized starting from MSU-type …