Computational biology—modeling of primary blast effects on the central nervous system

DF Moore, A Jérusalem, M Nyein, L Noels, MS Jaffee… - Neuroimage, 2009 - Elsevier
OBJECTIVES: Recent military conflicts in Iraq and Afghanistan have highlighted the wartime
effect of traumatic brain injury (TBI). The reason for the prominence of TBI in these particular …

Brain injuries from blast

CR Bass, MB Panzer, KA Rafaels, G Wood… - Annals of biomedical …, 2012 - Springer
Traumatic brain injury (TBI) from blast produces a number of conundrums. This review
focuses on five fundamental questions including:(1) What are the physical correlates for …

Quantitative proteomic profiling in brain subregions of mice exposed to open-field low-intensity blast reveals position-dependent blast effects

M Jackson, S Chen, P Liu, M Langenderfer, C Li… - Shock Waves, 2024 - Springer
The neurological consequences of combat blast-induced neurotrauma (BINT) pose
important clinical concerns for military service members and veterans. Previous studies have …

Traumatic brain injury and polytrauma in theaters of combat: the case for neurotrauma resuscitation?

FC Tortella, LY Leung - Shock, 2015 - journals.lww.com
Polytrauma associated with traumatic brain injury (TBI) is defined as a concurrent injury to
the brain and one or more body areas or organ systems that results in physical, cognitive …

[HTML][HTML] Blast induced brain injuries-a grand challenge in TBI research

M Risling - Frontiers in neurology, 2010 - frontiersin.org
The US government has initiated the largest coordinated research programs ever in
neurotrauma. The specific focus is to get insight in mechanisms and to provide better …

High-fidelity simulation of primary blast: direct effects on the head

TW Sawyer, Y Wang, DV Ritzel, T Josey… - Journal of …, 2016 - liebertpub.com
The role of primary blast in blast-induced traumatic brain injury (bTBI) is controversial in part
due to the technical difficulties of generating free-field blast conditions in the laboratory. The …

[引用][C] Blast brain injury risk

KA Rafaels - 2010

Isolated primary blast alters neuronal function with minimal cell death in organotypic hippocampal slice cultures

GB Effgen, EW Vogel III, KA Lynch, A Lobel… - Journal of …, 2014 - liebertpub.com
An increasing number of US soldiers are diagnosed with traumatic brain injury (TBI)
subsequent to exposure to blast. In the field, blast injury biomechanics are highly complex …

Blast traumatic brain injury in the rat using a blast overpressure model

AM Yarnell, MC Shaughness, ES Barry… - Current protocols in …, 2013 - Wiley Online Library
Traumatic brain injury (TBI) is a serious health concern for civilians and military populations,
and blast‐induced TBI (bTBI) has become an increasing problem for military personnel over …

Low-intensity blast wave model for preclinical assessment of closed-head mild traumatic brain injury in rodents

AF Logsdon, BP Lucke-Wold, RC Turner… - JoVE (Journal of …, 2020 - jove.com
Traumatic brain injury (TBI) is a large-scale public health problem. Mild TBI is the most
prevalent form of neurotrauma and accounts for a large number of medical visits in the …