[HTML][HTML] Intrahepatic CD69+ Vδ1 T cells re-circulate in the blood of patients with metastatic colorectal cancer and limit tumor progression
Background More than 50% of all patients with colorectal cancer (CRC) develop liver
metastases (CLM), a clinical condition characterized by poor prognosis and lack of reliable …
metastases (CLM), a clinical condition characterized by poor prognosis and lack of reliable …
Distinctive features of tumor-infiltrating γδ T lymphocytes in human colorectal cancer
ABSTRACT γδ T cells usually infiltrate many different types of cancer, but it is unclear
whether they inhibit or promote tumor progression. Moreover, properties of tumor-infiltrating …
whether they inhibit or promote tumor progression. Moreover, properties of tumor-infiltrating …
Hepatocellular carcinoma‐infiltrating γδ T cells are functionally defected and allogenic Vδ2+ γδ T cell can be a promising complement
In hepatocellular carcinoma (HCC), γδ T cells participate in mediating the anti‐tumour
response and are linked with a positive prognosis. However, these cells can become pro …
response and are linked with a positive prognosis. However, these cells can become pro …
Chemotherapy accelerates immune-senescence and functional impairments of Vδ2pos T cells in elderly patients affected by liver metastatic colorectal cancer
Human (gamma delta) γδ T cells are unconventional innate-like lymphocytes displaying a
broad array of anti-tumor activities with promising perspectives in cancer immunotherapy. In …
broad array of anti-tumor activities with promising perspectives in cancer immunotherapy. In …
Ex vivo expanded human circulating Vδ1 γδT cells exhibit favorable therapeutic potential for colon cancer
Gamma delta T (γδT) cells are innate-like lymphocytes with strong, MHC-unrestricted
cytotoxicity against cancer cells and show a promising prospect in adoptive cellular …
cytotoxicity against cancer cells and show a promising prospect in adoptive cellular …
Prognostic value of CD133+CD54+CD44+ circulating tumor cells in colorectal cancer with liver metastasis
C Fang, C Fan, C Wang, Q Huang, W Meng… - Cancer …, 2017 - Wiley Online Library
In the previous study, we had showed the expression of CD 133+ CD 54+ CD 44+ cellular
subpopulation of circulating tumor cells (CTC s) was significantly associated with liver …
subpopulation of circulating tumor cells (CTC s) was significantly associated with liver …
CD8+ CD226high T cells in liver metastases dictate the prognosis of colorectal cancer patients treated with chemotherapy and radical surgery
J Viot, S Abdeljaoued, A Vienot, E Seffar… - Cellular & molecular …, 2023 - nature.com
CD226 has been reported to participate in the rescue of CD8+ T cell dysfunction. In this
study, we aimed to assess the prognostic value of CD226 in tumor-infiltrating lymphocytes …
study, we aimed to assess the prognostic value of CD226 in tumor-infiltrating lymphocytes …
Anti-metastatic potential of human Vδ1+ γδ T cells in an orthotopic mouse xenograft model of colon carcinoma
C Devaud, B Rousseau, S Netzer, V Pitard… - Cancer Immunology …, 2013 - Springer
The role of human intraepithelial Vδ1+ γδ T cell cytotoxic effectors in the immune
surveillance against metastatic colon cancer has never been addressed, despite their …
surveillance against metastatic colon cancer has never been addressed, despite their …
[HTML][HTML] Investigation of the prognostic value of CD4 T cell subsets expanded from tumor-infiltrating lymphocytes of colorectal cancer liver metastases
M Kroemer, C Turco, L Spehner, J Viot… - … for immunotherapy of …, 2020 - ncbi.nlm.nih.gov
Background The positive role of CD8+ tumor-infiltrating lymphocytes (TIL) in patients with
colorectal cancer (CRC) has been well described but the prognostic value of CD4 T cell …
colorectal cancer (CRC) has been well described but the prognostic value of CD4 T cell …
Th17 cells inhibit CD8+ T cell migration by systematically downregulating CXCR3 expression via IL-17A/STAT3 in advanced-stage colorectal cancer patients
D Wang, W Yu, J Lian, Q Wu, S Liu, L Yang, F Li… - Journal of hematology & …, 2020 - Springer
Background CD8+ T cell trafficking to the tumor site is essential for effective colorectal
cancer (CRC) immunotherapy. However, the mechanism underlying CD8+ T cell infiltration …
cancer (CRC) immunotherapy. However, the mechanism underlying CD8+ T cell infiltration …