Physiological models for in vivo imaging and targeting the lymphatic system: Nanoparticles and extracellular vesicles
D Olmeda, D Cerezo-Wallis, E Castellano-Sanz… - Advanced Drug Delivery …, 2021 - Elsevier
Imaging of the lymphatic vasculature has gained great attention in various fields, not only
because lymphatic vessels act as a key draining system in the body, but also for their …
because lymphatic vessels act as a key draining system in the body, but also for their …
[HTML][HTML] Nanoparticles for lymph node-directed delivery
J Lee, S Kang, H Park, JG Sun, EC Kim, G Shim - Pharmaceutics, 2023 - mdpi.com
Lymph nodes are organs that control immune cells and provide a major pathway for primary
tumors to metastasize. A nanoparticles-based strategy has several advantages that make it …
tumors to metastasize. A nanoparticles-based strategy has several advantages that make it …
Advances in lymphatic imaging and drug delivery
SK Nune, P Gunda, BK Majeti, PK Thallapally… - Advanced drug delivery …, 2011 - Elsevier
Cancer remains the second leading cause of death after heart disease in the US. While
metastasized cancers such as breast, prostate, and colon are incurable, before their distant …
metastasized cancers such as breast, prostate, and colon are incurable, before their distant …
[HTML][HTML] Lymphatic drug delivery: therapy, imaging and nanotechnology
MS Cohen, ML Forrest - Advanced drug delivery reviews, 2011 - ncbi.nlm.nih.gov
The lymphatic system represents a relatively untapped biological highway to deliver
targeted drug molecules, nanoparticle drug-conjugates, imaging agents, vaccines and gene …
targeted drug molecules, nanoparticle drug-conjugates, imaging agents, vaccines and gene …
[HTML][HTML] Imaging technology of the lymphatic system
AK Polomska, ST Proulx - Advanced drug delivery reviews, 2021 - Elsevier
The lymphatic system plays critical roles in tissue fluid homeostasis and immunity and has
been implicated in the development of many different pathologies, ranging from …
been implicated in the development of many different pathologies, ranging from …
Expansion of the lymphatic vasculature in cancer and inflammation: new opportunities for in vivo imaging and drug delivery
Over the last 15 years, discovery of key growth factors and specific molecular markers for
lymphatic vessels has enabled a new era of molecular research on the lymphatic vascular …
lymphatic vessels has enabled a new era of molecular research on the lymphatic vascular …
Overcoming physiological barriers by nanoparticles for intravenous drug delivery to the lymph nodes
N Trac, EJ Chung - Experimental Biology and Medicine, 2021 - journals.sagepub.com
The lymph nodes are major sites of cancer metastasis and immune activity, and thus
represent important clinical targets. Although not as well-studied compared to subcutaneous …
represent important clinical targets. Although not as well-studied compared to subcutaneous …
Nano-sized drug delivery systems for lymphatic delivery
The lymphatic system plays important roles for immune responses, spreading cancer cells or
viruses and disseminating infections. Thus, targeting drugs, such as anticancer …
viruses and disseminating infections. Thus, targeting drugs, such as anticancer …
Lymphatic changes in cancer and drug delivery to the lymphatics in solid tumors
Although many solid tumors use the lymphatic system to metastasize, there are few
treatment options that directly target cancer present in the lymphatic system, and those that …
treatment options that directly target cancer present in the lymphatic system, and those that …
[HTML][HTML] The bright future of nanotechnology in lymphatic system imaging and imaging-guided surgery
Lymphatic system is identified the second vascular system after the blood circulation in
mammalian species, however the research on lymphatic system has long been hampered …
mammalian species, however the research on lymphatic system has long been hampered …