Genetic overlap and causality between substance use disorder and attention‐deficit and hyperactivity disorder

L Vilar‐Ribó, C Sánchez‐Mora, P Rovira… - American Journal of …, 2021 - Wiley Online Library
Substance use disorder (SUD) often co‐occur at high prevalence with other psychiatric
conditions. Among them, attention‐deficit and hyperactivity disorder (ADHD) is present in …

Genetic liability to ADHD and substance use disorders in individuals with ADHD

T Wimberley, E Agerbo, HT Horsdal, C Ottosen… - …, 2020 - Wiley Online Library
Aims 1) To investigate whether genetic liability to attention‐deficit/hyperactivity disorder
(ADHD), indexed by polygenic risk scores for ADHD (PRS‐ADHD), is associated with …

Dopamine and serotonin genetic risk scores predicting substance and nicotine use in attention deficit/hyperactivity disorder

AP Groenman, CU Greven… - Addiction …, 2016 - Wiley Online Library
Individuals with attention deficit/hyperactivity disorder (ADHD) are at increased risk of
developing substance use disorders (SUDs) and nicotine dependence. The co‐occurrence …

Genetics of substance use disorders: a review

JD Deak, EC Johnson - Psychological medicine, 2021 - cambridge.org
Substance use disorders (SUDs) are prevalent and result in an array of negative
consequences. They are influenced by genetic factors (h2=~ 50%). Recent years have …

[HTML][HTML] A common genetic network underlies substance use disorders and disruptive or externalizing disorders

M Arcos-Burgos, JI Vélez, BD Solomon, M Muenke - Human Genetics, 2012 - Springer
Here we summarize evidence obtained by our group during the last two decades, and
contrasted it with a review of related data from the available literature to show that …

Attention-deficit/hyperactivity disorder and lifetime cannabis use: genetic overlap and causality

M Soler Artigas, C Sánchez-Mora, P Rovira… - Molecular …, 2020 - nature.com
Attention-deficit/hyperactivity disorder (ADHD) is a severely impairing neurodevelopmental
disorder with a prevalence of 5% in children and adolescents and of 2.5% in adults …

Genetic and environmental contributions to the association between attention deficit hyperactivity disorder and alcohol dependence in adulthood: A large population …

AJ Capusan, P Bendtsen… - American Journal of …, 2015 - Wiley Online Library
Previous research indicates that attention deficit hyperactivity disorder (ADHD) frequently co‐
occurs with alcohol dependence; however, the extent to which shared genetic risk factors …

[HTML][HTML] Shared and unique genetic contributions to attention deficit/hyperactivity disorder and substance use disorders: a pilot study of six candidate genes

PJ Carpentier, AA Vasquez, M Hoogman… - European …, 2013 - Elsevier
The shared genetic basis of attention deficit/hyperactivity disorder (ADHD) and substance
use disorders (SUDs) was explored by investigating the association of candidate risk factors …

Genetic influences on ADHD symptom dimensions: Examination of a priori candidates, gene‐based tests, genome‐wide variation, and SNP heritability

LC Bidwell, JC Gray, J Weafer… - American Journal of …, 2017 - Wiley Online Library
Although the heritability of ADHD is estimated to be high, identifying specific genetic markers
remains challenging. Most studies to date have examined the genetic basis of ADHD by …

Examining the association between attention deficit hyperactivity disorder and substance use disorders: A familial risk analysis

AM Yule, MK Martelon, SV Faraone, N Carrellas… - Journal of psychiatric …, 2017 - Elsevier
Objective The main aim of this study was to use familial risk analysis to examine the
association between attention deficit hyperactivity disorder (ADHD) and substance use …