[HTML][HTML] Identifying the target cells and mechanisms of Merkel cell polyomavirus infection

W Liu, R Yang, AS Payne, RM Schowalter… - Cell host & …, 2016 - cell.com
Infection with Merkel cell polyomavirus (MCPyV) can lead to Merkel cell carcinoma (MCC), a
lethal form of skin cancer. However, the skin cell type productively infected by MCPyV …

Merkel cell polyomavirus infection and Merkel cell carcinoma

W Liu, M MacDonald, J You - Current opinion in virology, 2016 - Elsevier
Highlights•MCPyV infection is highly prevalent in the general population.•In elderly and
immunosuppressed individuals, MCPyV can cause Merkel cell carcinoma.•LT and sT …

Characterization of molecular mechanisms driving Merkel cell polyomavirus oncogene transcription and tumorigenic potential

JF Yang, W Liu, J You - PLoS Pathogens, 2023 - journals.plos.org
Merkel cell polyomavirus (MCPyV) is associated with approximately 80% of cases of Merkel
cell carcinoma (MCC), an aggressive type of skin cancer. The incidence of MCC has tripled …

From Merkel cell polyomavirus infection to Merkel cell carcinoma oncogenesis

NA Krump, J You - Frontiers in microbiology, 2021 - frontiersin.org
Merkel cell polyomavirus (MCPyV) infection causes near-ubiquitous, asymptomatic infection
in the skin, but occasionally leads to an aggressive skin cancer called Merkel cell carcinoma …

Epidemiology of Merkel cell polyomavirus infection and Merkel cell carcinoma

S Silling, A Kreuter, T Gambichler, T Meyer… - Cancers, 2022 - mdpi.com
Simple Summary Merkel cell polyomavirus (MCPyV) is a widespread virus that is present on
human skin. Infection occurs early in life, and up to 90% of adults have antibodies against …

[HTML][HTML] Distinct gene expression profiles of viral-and nonviral-associated merkel cell carcinoma revealed by transcriptome analysis

PW Harms, RM Patel, ME Verhaegen… - Journal of Investigative …, 2013 - Elsevier
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine tumor with high
mortality rates. Merkel cell polyomavirus (MCPyV), identified in the majority of MCCs, may …

Epigenetic dysregulations in merkel cell polyomavirus-driven merkel cell carcinoma

JC Rotondo, C Mazziotta, C Lanzillotti… - International Journal of …, 2021 - mdpi.com
Merkel cell polyomavirus (MCPyV) is a small DNA virus with oncogenic potential. MCPyV is
the causative agent of Merkel Cell Carcinoma (MCC), a rare but aggressive tumor of the …

Merkel cell polyomavirus: molecular insights into the most recently discovered human tumour virus

G Stakaitytė, JJ Wood, LM Knight, H Abdul-Sada… - Cancers, 2014 - mdpi.com
A fifth of worldwide cancer cases have an infectious origin, with viral infection being the
foremost. One such cancer is Merkel cell carcinoma (MCC), a rare but aggressive skin …

Merkel Cell Polyomavirus Small T Antigen mRNA Level Is Increased following In Vivo UV-Radiation

A Mogha, A Fautrel, N Mouchet, N Guo, S Corre… - PLoS …, 2010 - journals.plos.org
Merkel cell carcinoma (MCC) is a rare but aggressive skin cancer involving Merkel cells.
Recently, a new human polyomavirus was implicated in MCC, being present in 80% of the …

Merkel cell polyomavirus small T antigen promotes pro-glycolytic metabolic perturbations required for transformation

C Berrios, M Padi, MA Keibler, DE Park, V Molla… - PLoS …, 2016 - journals.plos.org
Merkel cell polyomavirus (MCPyV) is an etiological agent of Merkel cell carcinoma (MCC), a
highly aggressive skin cancer. The MCPyV small tumor antigen (ST) is required for …