Simple Summary Neurodevelopmental disorders are typically attributed to abnormal brain
development. These disorders encompass a wide range of neuropsychiatric symptoms that …

Transcription factors regulate multiple processes during brain development and in the adult
brain, from brain patterning to differentiation and maturation of highly specialized neurons as …

B cell leukemia 11b (Bcl11b) is a zinc finger protein transcription factor with a multiplicity of
functions. It works as both a genetic suppressor and activator, acting directly, attaching to …

Intellectual disability (ID) is a common condition with considerable genetic heterogeneity.
Next-generation sequencing of large cohorts has identified an increasing number of genes …

Objective According to a recent report, the mutation of transcription factor gene BCL11B is
associated with the development of neurodevelopmental disorders and immune deficiency …

The transcription factor BCL11B is essential for development of the nervous and the immune
system, and Bcl11b deficiency results in structural brain defects, reduced learning capacity …

Purpose Heterozygous variants in BCL11A underlie an intellectual developmental disorder
with persistence of fetal hemoglobin (BCL11A-IDD, aka Dias-Logan syndrome). We sought …

The transcription factor BCL11B plays an essential role in the development of central
nervous system and T cell differentiation by regulating the expression of numerous genes …

B-cell leukemia/lymphoma 11B (Bcl11b) is a transcription factor showing predominant
expression in the striatum. To date, there are no known gene targets of Bcl11b in the …

Background Next‐generation sequencing has been invaluable to delineate the genetic
etiology of neurodevelopmental disorders (NDDs) in recent years. BCL11B, encoding …