Post-transcriptional regulation by RNA binding proteins can determine gene expression
levels and drive changes in cancer cell proteomes. Identifying mechanisms of protein-RNA …

A considerable number of genes that code for AU-rich mRNAs including cytokines, growth
factors, transcriptional factors, and certain receptors are involved in both chronic …

RNA-binding proteins (RBPs) are key regulators of posttranscriptional gene expression and
control many important biological processes including cell proliferation, development, and …

Genome integrity must be tightly preserved to ensure cellular survival and to deter the
genesis of disease. Endogenous and exogenous stressors that impose threats to genomic …

Defects in AU-rich elements (ARE)-mediated posttranscriptional control can lead to several
abnormal processes that underlie carcinogenesis. Here, we performed a systematic analysis …

AU-rich elements (AREs) comprise one of the most widely studied families of regulatory
RNA structures met in RNAs engaged in complex immunological reactions. A multitude of …

Trans-acting factors controlling mRNA fate are critical for the post-transcriptional regulation
of inflammation-related genes, as well as for oncogene and tumor suppressor expression in …

The AU-rich elements (AREs) are among the predominant cis-acting factors that exist
primarily in the 3'untranslated region (3'-UTR) of messenger RNAs (mRNAs) and regulate …

Adenylate/uridylate-rich element (ARE)-mediated mRNA turnover is an important regulatory
component of gene expression for innate and specific immunity, in the hematopoietic …

mRNA metabolism is tightly orchestrated by highly-regulated RNA Binding Proteins (RBPs)
that determine mRNA fate, thereby influencing multiple cellular functions across biological …