Arterial oxygenation in traumatic brain injury—relation to cerebral energy metabolism, autoregulation, and clinical outcome

TS Wettervik, H Engquist, T Howells… - Journal of intensive …, 2021 - journals.sagepub.com
Background: Ischemic and hypoxic secondary brain insults are common and detrimental in
traumatic brain injury (TBI). Treatment aims to maintain an adequate cerebral blood flow with …

Effect of hyperoxia on regional oxygenation and metabolism after severe traumatic brain injury: preliminary findings

J Nortje, JP Coles, I Timofeev, TD Fryer… - Critical care …, 2008 - journals.lww.com
Objective: To determine the effect of normobaric hyperoxia on cerebral metabolism in
patients with severe traumatic brain injury. Design: Prospective clinical investigation. Setting …

Association between early hyperoxia and worse outcomes after traumatic brain injury

M Brenner, D Stein, P Hu, J Kufera, M Wooford… - Archives of …, 2012 - jamanetwork.com
Objective To investigate the relationship between oxygenation and short-term outcomes in
patients with traumatic brain injury (TBI). Design Logistic regression analysis was used to …

Matching early arterial oxygenation to long-term outcome in severe traumatic brain injury: target values

AS Alali, N Temkin, MS Vavilala, AV Lele… - Journal of …, 2019 - thejns.org
OBJECTIVE The aim of this study was to examine the relationship between early arterial
oxygenation thresholds and long-term outcome after severe traumatic brain injury (TBI) …

Principles of cerebral oxygenation and blood flow in the neurological critical care unit

Brigham and Women's Hospital Neurosurgery Group … - Neurocritical care, 2006 - Springer
Cerebrovascular disease and trauma are leading causes of death in the United States. In
addition to the initial insult to the brain, disturbances of cerebral oxygenation and …

Tissue oxygen reactivity and cerebral autoregulation after severe traumatic brain injury

EW Lang, M Czosnyka, HM Mehdorn - Critical care medicine, 2003 - journals.lww.com
Tissue oxygen reactivity and cerebral autoregulation after s... : Critical Care Medicine Tissue
oxygen reactivity and cerebral autoregulation after severe traumatic brain injury* : Critical Care …

Significance of arterial hyperoxia and relationship with case fatality in traumatic brain injury: a multicentre cohort study

F Rincon, J Kang, M Vibbert, J Urtecho… - Journal of Neurology …, 2014 - jnnp.bmj.com
Objective In this retrospective multi-centre cohort study, we tested the hypothesis that
hyperoxia was not associated with higher in-hospital case fatality in ventilated traumatic …

Normobaric hyperoxia in traumatic brain injury: does brain metabolic state influence the response to hyperoxic challenge?

A Vilalta, J Sahuquillo, MA Merino, MA Poca… - Journal of …, 2011 - liebertpub.com
This study sought to investigate whether normobaric hyperoxia (NH) improves brain
oxygenation and brain metabolism in the early phase of severe and moderate traumatic …

[HTML][HTML] Brain tissue oxygenation and cerebral metabolic patterns in focal and diffuse traumatic brain injury

K Purins, A Lewén, L Hillered, T Howells… - Frontiers in …, 2014 - frontiersin.org
Introduction: Neurointensive care of traumatic brain injury (TBI) patients is currently based
on intracranial pressure (ICP) and cerebral perfusion pressure (CPP) targeted protocols …

Physiologic and functional outcome correlates of brain tissue hypoxia in traumatic brain injury

JJJ Chang, TS Youn, D Benson, H Mattick… - Critical care …, 2009 - journals.lww.com
Objective: Assess the prevalence of brain tissue hypoxia in patients with severe traumatic
brain injuries (TBI), and to characterize the relationship between brain tissue hypoxia and …