Ubiquitination is a stable, reversible posttranslational modification of target proteins by
covalent ligation of the small chaperone protein ubiquitin. Most commonly ubiquitination …

Protein ubiquitination is a stable, reversible post-translational modification, targeting
proteins for degradation/recycling by the 26S proteasome in a well-characterized enzymatic …

The omnipresent ubiquitin–proteasome system (UPS) is an ATP-dependent enzymatic
machinery that targets substrate proteins for degradation by the 26S proteasome by tagging …

Spermatogenesis is a prolonged and highly ordered physiological process that produces
haploid male germ cells through more than 40 steps and experiences dramatic …

The ubiquitin proteasome system (UPS) participates in many biological processes ranging
from cell cycle and antigen processing to cellular defense and signaling. Work of the last …

Despite decades of research, the mechanism by which the fertilizing spermatozoon
penetrates the mammalian vitelline membrane, the zona pellucida (ZP) remains one of the …

Sperm capacitation is a complex process endowing biological and biochemical changes to
a spermatozoon for a successful encounter with an oocyte. The present study focused on the …

Posttranslational modification by ubiquitination marks defective or outlived intracellular
proteins for proteolytic degradation by the 26S proteasome. The ATP‐dependent, covalent …

Protein ubiquitination is a stable, covalent post‐translational modification that alters protein
activity and/or targets proteins for proteolysis by the 26S proteasome. The E1‐type ubiquitin …

The 26S proteasome, which is a multi-subunit protease with specificity for substrate proteins
that are postranslationally modified by ubiquitination, has been implicated in acrosomal …