Human antigen R (HuR) functions as a major post-transcriptional regulator of gene
expression through its RNA-binding activity. HuR is composed by three RNA recognition …

The 3′ UTRs of mammalian HIF-1α and EGF mRNA contain several highly conserved AU-
rich elements (ARE) known to control the turnover of labile mRNAs by binding ARE-binding …

Background HuR, an RNA binding protein involved in the post-transcriptional regulation of a
wide spectrum of mRNAs, has been demonstrated to be a determinant of carcinogenesis …

Regulated gene expression at the post-transcriptional level in higher eukaryotes is based on
a network of interactions among RNA-binding proteins (RBPs) operating within multifactorial …

Altered expression of RNA-binding proteins modulates gene expression in association with
mRNAs encoding many proto-oncogenes, cytokines, chemokines, and proinflammatory …

The posttranslational modification of proteins critically influences many biological processes
and is a key mechanism that regulates the function of the RNA-binding protein Hu antigen R …

We report the antiapoptotic effect of RNA‐binding protein HuR, a critical regulator of the post‐
transcriptional fate of target transcripts. Among the most prominent mRNAs complexing with …

An increased expression and cytoplasmic abundance of the ubiquitous RNA binding protein
human antigen R (HuR) is critically implicated in the dysregulated control of post …

An important paradigm for post‐transcriptional regulation is the control of cytoplasmic mRNA
stability mediated by AU‐rich elements (AREs) in the 3′ untranslated region of transcripts …

Immunohistochemical analysis of paired tumor and normal tissue specimens revealed that
the expression and cytoplasmic abundance of the RNA-binding protein HuR increased with …