VEGFs, receptors and angiogenesis

T Veikkola, K Alitalo - Seminars in cancer biology, 1999 - Elsevier
Angiogenesis, the formation of new blood vessels from pre–-existing ones, is central for both
normal development and homeostasis as well as in certain pathological conditions. The …

Functions of the VEGF/VEGF receptor system in the vascular system

G Breier - Seminars in thrombosis and hemostasis, 2000 - thieme-connect.com
The vascular endothelial growth factor (VEGF)/VEGF receptor system plays a central
regulatory role in physiological and pathological angiogenesis. During embryogenesis, the …

The role of VEGF receptors in angiogenesis; complex partnerships

S Cebe-Suarez, A Zehnder-Fjällman… - Cellular and molecular …, 2006 - Springer
Vascular endothelial growth factors (VEGFs) regulate blood and lymphatic vessel
development and homeostasis but also have profound effects on neural cells. VEGFs are …

VEGF-receptor signal transduction

MJ Cross, J Dixelius, T Matsumoto… - Trends in biochemical …, 2003 - cell.com
The vascular endothelial growth factor (VEGF) family of ligands and receptors has been the
focus of attention in vascular biology for more than a decade. There is now a consensus that …

Signal transduction by vascular endothelial growth factor receptors

S Koch, S Tugues, X Li, L Gualandi… - Biochemical …, 2011 - portlandpress.com
VEGFs (vascular endothelial growth factors) control vascular development during
embryogenesis and the function of blood vessels and lymphatic vessels in the adult. There …

VEGF function in vascular pathogenesis

YS Ng, D Krilleke, DT Shima - Experimental cell research, 2006 - Elsevier
Vascular endothelial growth factor (VEGF) has proven to be the most critical angiogenic
factor identified to date; its discovery has transformed the field of angiogenesis research …

Vascular endothelial growth factor signaling pathways: therapeutic perspective

M Kowanetz, N Ferrara - Clinical Cancer Research, 2006 - AACR
The establishment of a vascular supply is one of the earliest and most important events
occurring during embryonic development. Growth and maturation of a functional vascular …

Vascular endothelial growth factors and receptors: anti-angiogenic therapy in the treatment of cancer

S Tugues, S Koch, L Gualandi, X Li… - Molecular aspects of …, 2011 - Elsevier
Vascular endothelial growth factors (VEGFs) are critical regulators of vascular and lymphatic
function during development, in health and in disease. There are five mammalian VEGF …

[PDF][PDF] Signal relays in the VEGF system

N Ortéga, H Hutchings, J Plouët - Front Biosci, 1999 - academia.edu
1. ABSTRACT A considerable progress has been made during the past years in elucidating
the molecular actors of angiogenesis. Vascular endothelial growth factor turned out to …

The role of VEGF in the regulation of physiological and pathological angiogenesis

N Ferrara - Mechanisms of angiogenesis, 2005 - Springer
The existence of angiogenic factors was initially postulated on the basis of the strong
neovascular response induced by transplanted tumors. Subsequently, it was shown that …