Modularized extracellular vesicles: the dawn of prospective personalized and precision medicine

SC Tao, SC Guo, CQ Zhang - Advanced Science, 2018 - Wiley Online Library
Extracellular vesicles (EVs) are ubiquitous nanosized membrane vesicles consisting of a
lipid bilayer enclosing proteins and nucleic acids, which are active in intercellular …

Engineered Extracellular Vesicles: Emerging Therapeutic Strategies for Translational Applications

JN Ziegler, C Tian - International Journal of Molecular Sciences, 2023 - mdpi.com
Extracellular vesicles (EVs) are small, membrane-bound vesicles used by cells to deliver
biological cargo such as proteins, mRNA, and other biomolecules from one cell to another …

Shedding light on extracellular vesicle biogenesis and bioengineering

F Teng, M Fussenegger - Advanced Science, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are biocompatible, nano‐sized secreted vesicles containing
many types of biomolecules, including proteins, RNAs, DNAs, lipids, and metabolites. Their …

Cellular uptake of engineered extracellular vesicles: biomechanisms, engineered strategies, and disease treatment

Q Xie, Y Hao, N Li, H Song, X Chen… - Advanced …, 2024 - Wiley Online Library
Abstract Extracellular vesicles (EVs), lipid‐enclosed nanosized membrane vesicles, are
regarded as new vehicles and therapeutic agents in intercellular communication. During …

Engineered extracellular vesicles as a targeted delivery platform for precision therapy

Y Sun, F Sun, W Xu, H Qian - Tissue Engineering and Regenerative …, 2023 - Springer
Extracellular vesicles (EVs)-based cell-free strategy has shown therapeutic potential in
tissue regeneration. Due to their important roles in intercellular communications and their …

Advances in therapeutic applications of extracellular vesicles

OPB Wiklander, MÁ Brennan, J Lötvall… - Science translational …, 2019 - science.org
Extracellular vesicles (EVs) are nanometer-sized, lipid membrane–enclosed vesicles
secreted by most, if not all, cells and contain lipids, proteins, and various nucleic acid …

Scalable production of extracellular vesicles and its therapeutic values: a review

CY Ng, LT Kee, ME Al-Masawa, QH Lee… - International Journal of …, 2022 - mdpi.com
Extracellular vesicles (EVs) are minute vesicles with lipid bilayer membranes. EVs are
secreted by cells for intercellular communication. Recently, EVs have received much …

Therapeutic potential of engineered extracellular vesicles

KI Mentkowski, JD Snitzer, S Rusnak, JK Lang - The AAPS journal, 2018 - Springer
Extracellular vesicles (EVs) comprise a heterogeneous group of small membrane vesicles,
including exosomes, which play a critical role in intracellular communication and regulation …

Advances of engineered extracellular vesicles-based therapeutics strategy

H Komuro, S Aminova, K Lauro… - Science and Technology …, 2022 - Taylor & Francis
Extracellular vesicles (EVs) are a heterogeneous population of lipid bilayer membrane-
bound vesicles which encapsulate bioactive molecules, such as nucleic acids, proteins, and …

Strategies for engineering of extracellular vesicles

AA Danilushkina, CC Emene, NA Barlev… - International journal of …, 2023 - mdpi.com
Extracellular vesicles (EVs) are membrane vesicles released by cells into the extracellular
space. EVs mediate cell-to-cell communication through local and systemic transportation of …