Objective—VEGF-ENZ7/PlGF molecules composed of Orf virus-derived VEGF-ENZ7 and
human PlGF1 were previously proven to be potent angiogenic factors stimulating …

Objective—Vascular endothelial growth factor (VEGF) plays critical roles in the regulation of
angiogenesis and lymphangiogenesis. However, tissue edema, hemorrhage, and …

Fibroblasts are the main cells of connective tissue and have pivotal roles in the proliferative
and maturation phases of wound healing. These cells can secrete various cytokines, growth …

VEGF family members play important roles in angiogenesis and vascular permeability.
VEGF-A-transgenic mice showed an increased vascularization with edema due to hyper …

Soluble receptors to vascular endothelial growth factor (VEGF) can inhibit its angiogenic
effect. Since angiogenesis is involved in wound repair, we hypothesized that adenovirus …

Vascular endothelial growth factor (VEGF) is a potent paracrine signal for initiating
angiogenesis. Although VEGF can bind to several cell surface receptors, VEGF receptor …

Objective: Vascular endothelial growth factor (VEGF) family members are critical regulators
of tissue repair and depending on their distinct pattern of receptor specificity can also …

Both VEGF (vascular endothelial growth factor)-A and Orf-virus-encoded VEGF-E bind and
activate VEGFR (VEGF receptor)-2; however, only VEGF-A binds VEGFR-1. To understand …

Vascular endothelial growth factor‐A (VEGF‐A) is strongly up‐regulated in wounded
cutaneous tissue and promotes repair‐associated angiogenesis. However, little is known …

Chronic wounds remain a serious clinical problem with insufficient therapeutic approaches.
In this study we investigated the dose dependency of rhVEGF165 in fibrin sealant in both …