Delivery of antigen to porcine dendritic cells by fusing antigen with porcine dendritic cells targeting peptide

T Xia, N Wang, Y Tang, Y Gao, C Gao, J Hao… - Frontiers in …, 2022 - frontiersin.org
Dendritic cells (DCs) are professional antigen-presenting cells that can recognize, capture,
and process antigens. Fusing molecules targeting DCs with antigens can effectively improve …

Human dendritic cell targeting peptide can be targeted to porcine dendritic cells to improve antigen capture efficiency to stimulate stronger immune response

T Xia, H Yang, Y Guo, T Guo, L Xin, Y Jiang… - Frontiers in …, 2022 - frontiersin.org
Dendritic cells (DCs) play a key role in the natural recognition of pathogens and subsequent
activation of adaptive immune responses due to their potent antigen-presenting ability …

Screening and identification of a chicken dendritic cell binding peptide by using a phage display library

S Ma, X Qiao, Y Xu, L Wang, H Zhou, Y Jiang… - Frontiers in …, 2019 - frontiersin.org
Dendritic cells (DCs), as antigen-presenting cells, can initiate adaptive immune responses
efficiently. Although the DC-targeting strategy has attracted more attention, relevant studies …

Oral Immunization against PEDV with Recombinant Lactobacillus casei Expressing Dendritic Cell-Targeting Peptide Fusing COE Protein of PEDV in Piglets

X Hou, X Jiang, Y Jiang, L Tang, Y Xu, X Qiao, M Liu… - Viruses, 2018 - mdpi.com
Porcine epidemic diarrhea (PED) is a highly contagious disease in newborn piglets. In our
previous study, a genetically engineered Lactobacillus casei oral vaccine (pPG-COE …

Oral recombinant Lactobacillus vaccine targeting the intestinal microfold cells and dendritic cells for delivering the core neutralizing epitope of porcine epidemic …

S Ma, L Wang, X Huang, X Wang, S Chen, W Shi… - Microbial Cell …, 2018 - Springer
Background Porcine epidemic diarrhea caused by porcine epidemic diarrhea virus (PEDV)
has led to serious economic losses to the swine industry worldwide. In this study, an oral …

Efficient priming of CD4 T cells by Langerin-expressing dendritic cells targeted with porcine epidemic diarrhea virus spike protein domains in pigs

S Subramaniam, D Cao, D Tian, QM Cao, C Overend… - Virus research, 2017 - Elsevier
Porcine epidemic diarrhea virus (PEDV) first emerged in the United States in 2013 causing
high mortality and morbidity in neonatal piglets with immense economic losses to the swine …

Antigen Targeting of Porcine Skin DEC205+ Dendritic Cells

EA Melgoza-González, M Reséndiz-Sandoval… - Vaccines, 2022 - mdpi.com
Dendritic cell (DC) targeting by DEC205+ cells effectively promotes the internalization of
antigens that may trigger a specific immune response. In this study, we evaluated the ability …

In vivo targeting of porcine reproductive and respiratory syndrome virus antigen through porcine DC-SIGN to dendritic cells elicits antigen-specific CD4T cell immunity …

S Subramaniam, P Piñeyro, D Tian, C Overend… - Vaccine, 2014 - Elsevier
Immunogenicity of protein subunit vaccines may be dramatically improved by targeting them
through antibodies specific to c-type lectin receptors (CLRs) of dendritic cells in mice, cattle …

Oral delivery of probiotics expressing dendritic cell-targeting peptide fused with porcine epidemic diarrhea virus COE antigen: a promising vaccine strategy against …

X Wang, L Wang, X Huang, S Ma, M Yu, W Shi, X Qiao… - Viruses, 2017 - mdpi.com
Porcine epidemic diarrhea virus (PEDV), an enteric coronavirus, is the causative agent of
porcine epidemic diarrhea (PED) that damages intestinal epithelial cells and results in …

Construction and immunogenicity analysis of Lactobacillus plantarum expressing a porcine epidemic diarrhea virus S gene fused to a DC-targeting peptide

KY Huang, GL Yang, YB Jin, J Liu, HL Chen, PB Wang… - Virus research, 2018 - Elsevier
Porcine epidemic diarrhea virus (PEDV) is one of the most important causative pathogens of
swine diarrhea, which is widely prevalent throughout the world and is responsible for …