A variety of CTLA4-Fc fusion proteins and anti-CTLA4 monoclonal antibody have been
approved. Given the shortcomings of macromolecular antibodies, recombinant proteins …

Trumpfheller C, Longhi MP, Caskey M, Idoyaga J, Bozzacco L, Keler T, Schlesinger SJ,
Steinman RM (The Rockefeller University, New York, NY; and Celldex Therapeutics …

Within the ruminant system, several possibilities exist to generate dendritic cells migrating
out from the tissue into the regional draining lymph nodes as afferent lymph dendritic cells …

The present study investigated the transcriptomic response of porcine dendritic cells (DC) to
innate stimulation in vitro and in vivo. The aim was to identify DC subset-specialization …

Background The cytotoxic T lymphocyte antigen 4 (CTLA4) represents an attractive ligand
for use in the targeting of antigens to dendritic cells (DCs). Studies have shown that CTLA4 …

Infectious bronchitis virus (IBV) is a highly contagious avian coronavirus. IBV causes
substantial worldwide economic losses in the poultry industry. Vaccination with live …

We report the immunogenicity of three dendrimeric peptide vaccine candidates for classical
swine fever virus (CSFV). Each dendrimeric construct contained four copies of a B-cell …

Because of their unsurpassed potency in presenting antigens to naive T cells, dendritic cells
are considered to be an important candidate in the development of immunotherapeutic …

As the major outer membrane protein (OMP) presents in the Pasteurella multocida
envelope, OmpH was frequently expressed for laboratory assessments of its immunogenicity …

Avian influenza viruses can be efficiently transmitted through mucous membranes, and
conventional vaccines are not effective in protecting against mucosal infection by influenza …