Objectives Cardiac surgery using cardiopulmonary bypass contributes to a robust systemic
inflammatory process. Local intrapericardial postsurgical inflammation is believed to trigger …

Objective There is a paucity of data on the inflammatory response that takes place in the
pericardial space after cardiac surgery. This study provides a comprehensive assessment of …

Background: The systemic inflammatory response after cardiac surgery is well studied. The
important role of local intrapericardial immune cells in cardiac injury and cardiac remodeling …

Increased Inflammation in Pericardial Fluid Persists 48 Hours After Cardiac Surgery | Circulation
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Objectives Cardiac surgery induces a systemic inflammatory reaction that has been
associated with postoperative mortality and morbidity. Many studies have characterized this …

Cardiac surgery has undergone a remarkable growth and expansion in the past decades,
allowing research to focus on perioperative homeostatic disruption. Cardiac surgery always …

Background Data from large cardiac surgery registries have been depicting a downward
trend of mortality and morbidities in the last 20 years. However, despite decades of medical …

Objective: Due to the combination of local trauma, extracorporeal circulation (ECC), and
pulmonary and myocardial reperfusion, cardiac surgery leads to substantial changes in the …

OBJECTIVES: Cytokines contribute to the development of the systemic inflammatory
response syndrome or multiple-organ failure frequently observed after cardiopulmonary …

Background Cardiopulmonary bypass (CPB) is an immuno-reactive state where neutrophils
are activated and accumulate in different tissues. Edema and tissue necrosis are the most …