The therapeutic potential of mesenchymal stem cells for cardiovascular diseases

Y Guo, Y Yu, S Hu, Y Chen, Z Shen - Cell Death & Disease, 2020 - nature.com
Mesenchymal stem cells (MSCs) are derived from a wide range of sources and easily
isolated and cultured. MSCs have the capacity for in vitro amplification and self-renewal, low …

Mesenchymal stem cells in cardiology

IA White, C Sanina, W Balkan, JM Hare - Mesenchymal Stem Cells …, 2016 - Springer
Cardiovascular disease (CVD) accounts for more deaths globally than any other single
disease. There are on average 1.5 million episodes of myocardial infarction (heart attack) …

Mesenchymal stem cell insights: prospects in cardiovascular therapy

SH Chou, SZ Lin, WW Kuo, P Pai, JY Lin… - Cell …, 2014 - journals.sagepub.com
Ischemic heart damage usually triggers cardiomyopathological remodeling and fibrosis, thus
promoting the development of heart functional failure. Mesenchymal stem cells (MSCs) are a …

Mesenchymal stem cells for the treatment of heart failure

S Ohnishi, H Ohgushi, S Kitamura… - International journal of …, 2007 - Springer
Heart failure is one of the most important cardiovascular health problems throughout the
world and has high mortality, and there is a need to develop more effective therapeutic …

Modification of mesenchymal stem cells for cardiac regeneration

H Song, BW Song, MJ Cha, IG Choi… - Expert Opinion on …, 2010 - Taylor & Francis
Importance of the field: Mesenchymal stem cells (MSCs) have the greatest potential for use
in cell-based therapy of human heart diseases, especially in myocardial infarcts. The …

Concise review: mesenchymal stem cells in cardiovascular regeneration: emerging research directions and clinical applications

M Majka, M Sułkowski, B Badyra… - Stem cells translational …, 2017 - academic.oup.com
Experimental and early clinical data suggest that, due to several unique properties,
mesenchymal stem cells (MSCs) may be more effective than other cell types for diseases …

Mesenchymal stem cells: biology, pathophysiology, translational findings, and therapeutic implications for cardiac disease

AR Williams, JM Hare - Circulation research, 2011 - Am Heart Assoc
Mesenchymal stem cells (MSCs) are a prototypical adult stem cell with capacity for self-
renewal and differentiation with a broad tissue distribution. Initially described in bone …

How to improve the survival of transplanted mesenchymal stem cell in ischemic heart?

L Li, X Chen, WE Wang, C Zeng - Stem Cells International, 2016 - Wiley Online Library
Mesenchymal stem cell (MSC) is an intensely studied stem cell type applied for cardiac
repair. For decades, the preclinical researches on animal model and clinical trials have …

Mesenchymal stem cell-based therapy for cardiovascular disease: progress and challenges

L Bagno, KE Hatzistergos, W Balkan, JM Hare - Molecular Therapy, 2018 - cell.com
Administration of mesenchymal stem cells (MSCs) to diseased hearts improves cardiac
function and reduces scar. These effects occur via stimulation of endogenous repair …

Emerging role for bone marrow derived mesenchymal stem cells in myocardial regenerative therapy

JM Zimmet, JM Hare - Basic research in cardiology, 2005 - Springer
Current treatments for ischemic cardiomyopathy are aimed toward minimizing the
deleterious consequences of diseased myocardium. The possibility of treating heart failure …