The Association between Life Stress and Abnormal Uric Acid Metabolism and Gout: Findings from a Large-Scale Population Cohort

Z Jiang, J Chen, S Wu, J Chen, C Wu, HY Kwan… - Jieyu and Wu, Siqi and … - papers.ssrn.com
Background: People do experience stress throughout their lifetime, and it is associated with
chronic diseases. However, it remains unclear whether life stress is associated with uric acid …

Multiple genetic loci influence serum urate levels and their relationship with gout and cardiovascular disease risk factors

Q Yang, A Köttgen, A Dehghan, AV Smith… - Circulation …, 2010 - Am Heart Assoc
Background—Elevated serum urate levels can lead to gout and are associated with
cardiovascular risk factors. We performed a genome-wide association study to search for …

Relationship between life events and serum uric acid in patients with hyperuricemia

Y MA, H CHEN - Chinese Journal of Endocrinology and …, 2020 - pesquisa.bvsalud.org
Objective@# To investigate the relationship between psychological stress related factors in
life events and serum uric acid levels in patients with hyperuricemia.@* Methods@# The life …

Association of three genetic loci with uric acid concentration and risk of gout: a genome-wide association study

A Dehghan, A Köttgen, Q Yang, SJ Hwang, WHL Kao… - The Lancet, 2008 - thelancet.com
Background Hyperuricaemia, a highly heritable trait, is a key risk factor for gout. We aimed to
identify novel genes associated with serum uric acid concentration and gout. Methods …

A U-Shape Association of Serum Uric Acid with Gout in US Adults

X Yan, T Sun, Z Zhao, R Luo, H Zhao, H Zhao… - Frontiers in Epidemiology - frontiersin.org
Serum uric acid (SUA) level is the strongest determinant of gout, and the relationship
between hyperuricemia and gout has been found. However, the association between the …

Are polymorphisms affecting serum urate, renal urate handling and alcohol intake associated with co-morbidities in gout cases? A case–control study using data from …

G Sandoval-Plata, K Morgan, A Abhishek - Rheumatology International, 2022 - Springer
To examine the association between common comorbidities, eGFR and loci involved in the
hyperuricaemia-gout transition. This study was conducted in people with gout from the UK …

Independent and conjoint associations of gout and hyperuricaemia with total and cardiovascular mortality

AG Stack, A Hanley, LF Casserly… - … Journal of Medicine, 2013 - academic.oup.com
Background: Gout and serum uric acid are associated with mortality but their simultaneous
contributions have not been fully evaluated in the general population. Purpose: To explore …

Gender-specific risk factors for incident gout: a prospective cohort study

JH Chen, WT Yeh, SY Chuang, YY Wu, WH Pan - Clinical rheumatology, 2012 - Springer
Previous reports suggested that gout incidence increased with serum uric acid (sUA) level.
In addition to sUA, we aimed to examine the gender-specific risk factors for incident gout. A …

A u-shape association of serum uric acid with gout in US adults

Y Xinmiao, S Taolan, Z Zixuan, L Yanrong, Z Hanbing… - medRxiv, 2022 - medrxiv.org
Background Serum uric acid (SUA) level is the strongest determinant of gout, and the
relationship between hyperuricemia and gout has been found. However, the association …

Healthy lifestyle counteracts the risk effect of genetic factors on incident gout: a large population-based longitudinal study

Y Zhang, R Yang, A Dove, X Li, H Yang, S Li, J Wang… - BMC medicine, 2022 - Springer
Background Risk genes linked to the development of gout have been identified, and lifestyle
factors are related to gout risk. It remains unclear whether healthy lifestyle factors can …