Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in smokers in the United States: NHANES 2007–2008
Y Xia, JT Bernert, RB Jain, DL Ashley, JL Pirkle - Biomarkers, 2011 - Taylor & Francis
The tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), a
metabolite of the tobacco-specific nitrosamine (TSNA) 4-(methylnitrosamino)-1-(3-pyridyl)-1 …
metabolite of the tobacco-specific nitrosamine (TSNA) 4-(methylnitrosamino)-1-(3-pyridyl)-1 …
Assessing exposure to tobacco-specific carcinogen NNK using its urinary metabolite NNAL measured in US population: 2011–2012
B Wei, BC Blount, B Xia, L Wang - Journal of exposure science & …, 2016 - nature.com
Carcinogenic tobacco-specific nitrosamines (TSNAs) such as 4-(methylnitrosamino)-1-(3-
pyridyl)-1-butanone (NNK) are found only in tobacco and derived products. Food and Drug …
pyridyl)-1-butanone (NNK) are found only in tobacco and derived products. Food and Drug …
Urine concentrations of a tobacco-specific nitrosamine carcinogen in the US population from secondhand smoke exposure
JT Bernert, JL Pirkle, Y Xia, RB Jain, DL Ashley… - … , biomarkers & prevention, 2010 - AACR
Background: The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-
butanone (NNK) and its reduction product in the body, 4-(methylnitrosamino)-1-(3-pyridyl)-1 …
butanone (NNK) and its reduction product in the body, 4-(methylnitrosamino)-1-(3-pyridyl)-1 …
Tobacco-specific nitrosamines (NNAL, NNN, NAT, and NAB) exposures in the US Population Assessment of Tobacco and Health (PATH) Study Wave 1 (2013–2014)
B Xia, BC Blount, T Guillot, C Brosius… - Nicotine and …, 2021 - academic.oup.com
Introduction The tobacco-specific nitrosamines (TSNAs) are an important group of
carcinogens found in tobacco and tobacco smoke. To describe and characterize the levels …
carcinogens found in tobacco and tobacco smoke. To describe and characterize the levels …
Effect of differing levels of tobacco-specific nitrosamines in cigarette smoke on the levels of biomarkers in smokers
DL Ashley, RJ O'Connor, JT Bernert, CH Watson… - … , biomarkers & prevention, 2010 - AACR
Background: Smokers are exposed to significant doses of carcinogens, including tobacco-
specific nitrosamines (TSNA). Previous studies have shown significant global differences in …
specific nitrosamines (TSNA). Previous studies have shown significant global differences in …
Metabolism of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone to its biomarker total NNAL in smokeless tobacco users
SS Hecht, SG Carmella, I Stepanov, J Jensen… - … Biomarkers & Prevention, 2008 - AACR
Abstract The tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone
(NNK) is one of the most abundant carcinogens in smokeless tobacco products. NNK uptake …
(NNK) is one of the most abundant carcinogens in smokeless tobacco products. NNK uptake …
Subpicogram per milliliter determination of the tobacco-specific carcinogen metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in human urine using liquid …
P Jacob III, C Havel, DH Lee, L Yu, MD Eisner… - Analytical …, 2008 - ACS Publications
Exposure to secondhand tobacco smoke (SHS) has been linked to increased risk for a
number of diseases, including lung cancer. The tobacco-specific nitrosamine 4 …
number of diseases, including lung cancer. The tobacco-specific nitrosamine 4 …
Biomonitoring of environmental tobacco smoke (ETS)-related exposure to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)
M Meger, I Meger-Kossien, K Riedel, G Scherer - Biomarkers, 2000 - Taylor & Francis
The exposure of non-smokers to the tobacco-specific N-nitrosamine 4-(N-
methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a rodent lung carcinogen, was …
methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a rodent lung carcinogen, was …
TSNA exposure: levels of NNAL among Canadian tobacco users
CD Czoli, D Hammond - Nicotine & Tobacco Research, 2015 - academic.oup.com
Introduction: Tobacco smoke contains more than 7,000 chemicals, including known
carcinogens, such as tobacco-specific nitrosamines (TSNAs). TSNA levels in cigarettes vary …
carcinogens, such as tobacco-specific nitrosamines (TSNAs). TSNA levels in cigarettes vary …
Development of a method for the determination of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in urine of nonsmokers and smokers using liquid chromatography …
H Hou, X Zhang, Y Tian, G Tang, Y Liu, Q Hu - Journal of pharmaceutical …, 2012 - Elsevier
4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) is an efficient biomarker of tobacco-
specific carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). The ability to …
specific carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). The ability to …