Expression of human GFRα-1 (GDNF receptor) at the neuromuscular junction and myelinated nerves

A Hase, H Suzuki, K Arahata, C Akazawa - Neuroscience letters, 1999 - Elsevier
Motor neurons have been known to require a wide variety of neurotrophic factors for their
survival. As one of the target-derived trophic factors, glial cell line-derived neurotrophic …

Prominent expression of glial cell line–derived neurotrophic factor in human skeletal muscle

H Suzuki, A Hase, Y Miyata, K Arahata… - Journal of …, 1998 - Wiley Online Library
Glial cell line–derived neurotrophic factor (GDNF) has been shown to exert neurotrophic
effects on motor neurons as well as mesencephalic dopaminergic neurons. Because GDNF …

GDNF expression is increased in denervated human skeletal muscle

DC Lie, J Weis - Neuroscience letters, 1998 - Elsevier
Glial cell line derived neurotrophic factor (GDNF) is a potent trophic factor for several
subpopulations of neurons including motor neurons. Two different transcripts of the GDNF …

Up-regulation of glial cell line-derived neurotrophic factor (GDNF) expression in regenerating muscle fibers in neuromuscular diseases

H Suzuki, A Hase, BY Kim, Y Miyata, I Nonaka… - Neuroscience …, 1998 - Elsevier
Glial cell line-derived neurotrophic factor (GDNF) has been shown to exert a target-derived
trophic factor for motor neurons. Immunohistochemical analyses revealed that expression of …

Glial cell line neurotrophic factor-family receptor α-1 is present in central neurons with distinct phenotypes

A Sarabi, BJ Hoffer, L Olson, M Morales - Neuroscience, 2003 - Elsevier
Glial cell line neurotrophic factor (GDNF) is a potent survival factor for several types of
neurons. GDNF binds with high affinity to the GDNF-family receptor α-1 (GFRα-1) which is …

Characterization of glial cell line‐derived neurotrophic factor family receptor α‐1 in peripheral nerve Schwann cells

A Hase, F Saito, H Yamada, K Arai… - Journal of …, 2005 - Wiley Online Library
Glial cell line‐derived neurotrophic factor (GDNF) family receptor α‐1 (GFRα‐1) is a receptor
component of GDNF that associates with and activates the tyrosine kinase receptor Ret. To …

[HTML][HTML] GDNF synthesis, signaling, and retrograde transport in motor neurons

AF Cintrón-Colón, G Almeida-Alves, AM Boynton… - Cell and tissue …, 2020 - Springer
Glial cell line–derived neurotrophic factor (GDNF) is a 134 amino acid protein belonging in
the GDNF family ligands (GFLs). GDNF was originally isolated from rat glial cell lines and …

Differential regulation of mRNAs for GDNF and its receptors Ret and GDNFRα after sciatic nerve lesion in the mouse

P Naveilhan, WM ElShamy… - European Journal of …, 1997 - Wiley Online Library
Glial cell line‐derived neurotrophic factor (GDNF), first characterized for its effect on
dopamine uptake in central dopaminergic neurons, appears to be a powerful neurotrophic …

GDNF is regulated in an activity‐dependent manner in rat skeletal muscle

EA Wehrwein, EM Roskelley… - Muscle & Nerve: Official …, 2002 - Wiley Online Library
Glial cell line–derived neurotrophic factor (GDNF) is produced by skeletal muscle and affects
peripheral motor neurons. Elevated expression of GDNF in skeletal muscle leads to …

Novel functions and signalling pathways for GDNF

H Sariola, M Saarma - Journal of cell science, 2003 - journals.biologists.com
Glial-cell-line-derived neurotrophic factor (GDNF) was originally identified as a survival
factor for midbrain dopaminergic neurons. GDNF and related ligands, neurturin (NRTN) …