Coronavirus disease-2019 (COVID-19), a potentially lethal respiratory illness caused by the
coronavirus SARS-CoV-2, emerged in the end of 2019 and has since spread aggressively …

Cell penetration after recognition of the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) virus by the ACE2 receptor and the fusion of its viral envelope membrane …

The receptor binding and proteolysis of Spike of SARS-CoV-2 release its S2 subunit to
rearrange and catalyze viral-cell fusion. This deploys the fusion peptide for insertion into the …

The emerging and re-emerging viral diseases are continuous threats to the wellbeing of
human life. Previous outbreaks of Severe Acute Respiratory Syndrome (SARS) and Middle …

SARS‐CoV‐2 may enter target cells through the process of membrane fusion at either the
plasma (~ pH 7.4–7.0) or endosomal (~ pH 6.5–5.0) membrane in order to deliver its genetic …

Membrane fusion, a key step in the early stages of virus propagation, allows the release of
the viral genome in the host cell cytoplasm. The process is initiated by fusion peptides that …

Infection of human cells by the severe acute respiratory syndrome coronavirus 2 (SARS-
CoV2) relies on its binding to a specific receptor and subsequent fusion of the viral and host …

During infection the SARS-CoV-2 virus fuses its viral envelope with cellular membranes of
its human host. The viral spike (S) protein mediates both the initial contact with the host cell …

Coronaviruses (CoVs) are a major infectious disease threat and include the pathogenic
human pathogens of zoonotic origin: severe acute respiratory syndrome CoV (SARS-CoV) …

The pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has resulted in an unprecedented setback …