Up to date, effective antivirals have not been widely available for treating COVID-19. In this
study, we identify a dual-functional cross-linking peptide 8P9R which can inhibit the two …

Blocking Coronavirus 19 Infection via the SARS-CoV-2 Spike Protein: Initial Steps | ACS
Medicinal Chemistry Letters Recently Viewedclose modal Pair your accounts. Export articles to …

Over 50 peptides, which were known to inhibit SARS-CoV-1, were computationally screened
against the receptor-binding domain (RBD) of the spike protein of SARS-CoV-2. Based on …

The emergence of highly transmissible SARS-CoV-2 variants has led to the waves of the
resurgence of COVID-19 cases. Effective antivirals against variants are required. Here we …

The COVID-19 pandemic has prompted a rapid response in vaccine and drug development.
Herein, we modeled a complete membrane-embedded SARS-CoV-2 spike glycoprotein and …

The SARS-CoV-2 virion responsible for the current world-wide pandemic COVID-19 has a
characteristic Spike protein (S) on its surface that embellishes both a prefusion state and …

The COVID-19 pandemic and concomitant lockdowns presented a global health challenge
and triggered unprecedented research efforts to elucidate the molecular mechanisms and …

Current COVID-19 vaccines and many clinical diagnostics are based on the structure and
function of the SARS-CoV-2 spike ectodomain. Using hydrogen–deuterium exchange …

Beginning from the end of 2019, the severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) pandemic swept all over the world and is still afflicting the whole global …

We investigate binding of linoleate and other potential ligands to the recently discovered
fatty acid binding site in the SARS‐CoV‐2 spike protein, using docking and molecular …