The emergence and rapid spreading of SARS-CoV-2 variants of concern (VOCs) have
posed a great challenge to the efficacy of vaccines and therapeutic antibodies, calling for …

The COVID-19 pandemic, caused by SARS-CoV-2, has led to substantial morbidity,
mortality, and disruption globally. Cellular entry of SARS-CoV-2 is mediated by the viral …

Containment of the COVID-19 pandemic requires reducing viral transmission. Severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is initiated by membrane fusion …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is continuously evolving.
Although several vaccines were approved, this pandemic is still a major threat to public life …

Membrane recognition by viral spike proteins is critical for infection. Here we show the host
cell membrane-binding surfaces of severe acute respiratory syndrome coronavirus 2 (SARS …

Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is initiated by
binding of the viral Spike protein to host receptor angiotensin-converting enzyme 2 (ACE2) …

In order to complete the fusion process of SARS-CoV virus, several regions of the S2 virus
envelope glycoprotein are necessary. Recent studies have identified three membrane-active …

Mutations in the spike protein generated a highly infectious and transmissible D614G
variant, which is present in newly evolved fast-spreading variants. The D614G, Alpha, Beta …

The 2019 novel coronavirus (2019-nCoV) is currently causing a widespread outbreak
centered on Hubei province, China and is a major public health concern. Taxonomically …

Our evolutionary and structural analyses revealed that the severe acute respiratory
syndrome (SARS) coronavirus 2 (SARS-CoV-2) spike gene is a complex mosaic resulting …