Nonstructural protein 7 and 8 complexes of SARS‐CoV‐2
The pandemic outbreak of coronavirus disease 2019 (COVID‐19) across the world has led
to millions of infection cases and caused a global public health crisis. Current research …
to millions of infection cases and caused a global public health crisis. Current research …
ORFeome phage display reveals a major immunogenic epitope on the S2 subdomain of SARS-CoV-2 spike protein
R Ballmann, SK Hotop, F Bertoglio, S Steinke… - Viruses, 2022 - mdpi.com
The development of antibody therapies against SARS-CoV-2 remains a challenging task
during the ongoing COVID-19 pandemic. All approved therapeutic antibodies are directed …
during the ongoing COVID-19 pandemic. All approved therapeutic antibodies are directed …
Deducing the N-and O-glycosylation profile of the spike protein of novel coronavirus SARS-CoV-2
The current emergence of the novel coronavirus pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) demands the development of new …
respiratory syndrome coronavirus 2 (SARS-CoV-2) demands the development of new …
Structural features of coronavirus SARS-CoV-2 spike protein: Targets for vaccination
A Sternberg, C Naujokat - Life sciences, 2020 - Elsevier
Various human pathogenic viruses employ envelope glycoproteins for host cell receptor
recognition and binding, membrane fusion and viral entry. The spike (S) glycoprotein of …
recognition and binding, membrane fusion and viral entry. The spike (S) glycoprotein of …
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
The outbreak of a novel coronavirus (2019-nCoV) represents a pandemic threat that has
been declared a public health emergency of international concern. The CoV spike (S) …
been declared a public health emergency of international concern. The CoV spike (S) …
Mutations in the B. 1.1. 7 SARS-CoV-2 spike protein reduce receptor-binding affinity and induce a flexible link to the fusion peptide
The B. 1.1. 7 variant of the SARS-CoV-2 virus shows enhanced infectiousness over the wild
type virus, leading to increasing patient numbers in affected areas. Amino acid exchanges …
type virus, leading to increasing patient numbers in affected areas. Amino acid exchanges …
Tryptophan-dependent membrane interaction and heteromerization with the internal fusion peptide by the membrane proximal external region of SARS-CoV spike …
Y Liao, SM Zhang, TL Neo, JP Tam - Biochemistry, 2015 - ACS Publications
The spike (S) protein of severe acute respiratory syndrome-associated CoV (SARS-CoV)
mediates membrane fusion and viral entry. These events involve structural rearrangements …
mediates membrane fusion and viral entry. These events involve structural rearrangements …
Tectonic conformational changes of a coronavirus spike glycoprotein promote membrane fusion
The tremendous pandemic potential of coronaviruses was demonstrated twice in the past
few decades by two global outbreaks of deadly pneumonia. The coronavirus spike (S) …
few decades by two global outbreaks of deadly pneumonia. The coronavirus spike (S) …
In silico discovery of small molecule modulators targeting the Achilles' heel of SARS-CoV-2 spike protein
Q Wang, F Meng, Y Xie, W Wang, Y Meng… - ACS Central …, 2023 - ACS Publications
The spike protein of SARS-CoV-2 has been a promising target for developing vaccines and
therapeutics due to its crucial role in the viral entry process. Previously reported cryogenic …
therapeutics due to its crucial role in the viral entry process. Previously reported cryogenic …
Assessing antigen structural integrity through glycosylation analysis of the SARS-CoV-2 viral spike
J Brun, S Vasiljevic, B Gangadharan… - ACS central …, 2021 - ACS Publications
Severe acute respiratory syndrome coronavirus 2 is the causative pathogen of the COVID-
19 pandemic which as of March 29, 2021, has claimed 2 776 175 lives worldwide. Vaccine …
19 pandemic which as of March 29, 2021, has claimed 2 776 175 lives worldwide. Vaccine …