In vertebrates, biomineralization is a feature considered unique to mature osteoblasts and
odontoblasts by which they synthesize hydroxyapatite (HAP), which is deposited in the …

Humans utilise biomineralisation in the formation of bone and teeth. Human
biomineralisation processes are defined by the transformation of an amorphous phosphate …

The ubiquitous process of biological mineralization has preoccupied scientists for centuries.
In 1849 Quekett [1] wrote a paper entitled ''On the Intimate Structure of Bone, as Composing …

THE MECHANISMS BY WHICH MINERALIZED TISSUES such as bone acquire and
regulate their mineral component are complex. The process of mineralization can be divided …

Through evolution, vertebrates have “chosen” the calcium phosphate mineral apatite to
mineralize their teeth and bones. This article describes the key characteristics of apatite in …

Mineralization is a ubiquitous process in the animal kingdom and is fundamental to human
development and health. Dysfunctional or aberrant mineralization leads to a variety of …

Biomineralization is the process by which living organisms generate organized mineral
crystals. In human cells, this phenomenon culminates with the formation of hydroxyapatite …

Hydroxyapatite (HAP) is the major biomineral of bone. Despite the large number of studies
addressing HAP formation, a fundamental understanding of the critical roles of HAP-forming …

In contrast to physiologic biomineralization occurring in bones, teeth and otoconia in
vertebrates, calcification of soft tissues occurs in many pathologic conditions. Although …

Since its characterization two decades ago, the phosphatase PHOSPHO1 has been the
subject of an increasing focus of research. This work has elucidated PHOSPHO1's central …