Rationale Noradrenaline (NE) is closely related to attentive performance and impulsive
control. However, the potential sex differences regarding attention and impulsivity under the …

Rationale Atomoxetine, reboxetine and methylphenidate all act at the noradrenaline
transporter (NAT) and atomoxetine and methylphenidate are licensed for the treatment of …

Rationale Noradrenergic dysfunction is associated with disorders of impulsivity and
inattention. The rodent continuous performance test (rCPT) quantifies changes in attention …

Rationale The ability to detect unpredictable cues can involve stimulus-elicited orienting of
attention (bottom-up processing); however, in many settings, target onset is partially …

Rationale Impulsivity is associated with a number of psychiatric disorders, most notably
attention deficit/hyperactivity disorder (ADHD). Drugs that augment catecholamine function …

Rationale Atomoxetine is a noradrenaline re-uptake inhibitor licensed for the treatment of
adult and childhood attention deficit hyperactivity disorder. Although atomoxetine has …

Atomoxetine, a noradrenaline reuptake inhibitor (NRI), which is a non-stimulating medicine
that is used for the treatment of patients with attention deficit hyperactivity disorder (ADHD) …

Rationale High levels of impulsivity are a core symptom of psychiatric disorders such as
ADHD, mania, personality disorders and drug addiction. The effectiveness of drugs targeting …

Background Work in humans has shown that impulsivity can be advantageous in certain
settings. However, evidence for so-called functional impulsivity is lacking in experimental …

Rationale Previous data indicate that depletion of cortical noradrenaline (NA) impairs
performance of an attentional five-choice serial reaction time task (5CSRT) under certain …