On the improvement of inhibitory response control and visuospatial attention by indirect and direct adrenoceptor agonists

T Pattij, D Schetters, ANM Schoffelmeer… - …, 2012 - Springer
Rationale The clinical efficacy of the monoamine and noradrenaline transporter inhibitors
methylphenidate and atomoxetine in attention deficit/hyperactivity disorder implicates …

The use of reaction time distributions to study attention in male rats: the effects of atomoxetine and guanfacine

ZV Redding, P Chawla, KE Sabol - Psychopharmacology, 2019 - Springer
Rationale Norepinephrine (NE) is involved in the control of sustained attention. Studies of
sustained attention in humans include measures of reaction time (RT) and RT variability …

Impaired flexibility in decision making in rats after administration of the pharmacological stressor yohimbine

AL Schwager, AK Haack, SA Taha - Psychopharmacology, 2014 - Springer
Rationale Stress-induced disruption of decision making has been hypothesized to contribute
to drug-seeking behaviors and addiction. Noradrenergic signaling plays a central role in …

Noradrenergic modulation of risk/reward decision making

DR Montes, CM Stopper, SB Floresco - Psychopharmacology, 2015 - Springer
Rationale Catecholamine transmission modulates numerous cognitive and reward-related
processes that can subserve more complex functions such as cost/benefit decision making …

Atomoxetine and reward size equally improve task engagement and perceptual decisions but differently affect movement execution

K Kaduk, T Henry, J Guitton, M Meunier, D Thura… - …, 2023 - Elsevier
Our ability to engage and perform daily activities relies on balancing the associated benefits
and costs. Rewards, as benefits, act as powerful motivators that help us stay focused for …

The effects of serotonin and/or noradrenaline reuptake inhibitors on impulsive-like action assessed by the three-choice serial reaction time task: a simple and valid …

I Tsutsui-Kimura, Y Ohmura, T Izumi… - Behavioural …, 2009 - journals.lww.com
Impulsivity is a pathological symptom in several psychiatric disorders, underscoring the
need for animal models of impulsive action to develop a brief screening method for novel …

Characterization of amphetamine, methylphenidate, nicotine, and atomoxetine on measures of attention, impulsive action, and motivation in the rat: implications for …

GA Higgins, LB Silenieks, C MacMillan… - Frontiers in …, 2020 - frontiersin.org
Amphetamine (AMP), methylphenidate (MPH), and atomoxetine (ATX) are approved
treatments for ADHD, and together with nicotine (NIC), represent pharmacological agents …

The 5-HT1A/1B-receptor agonist eltoprazine increases both catecholamine release in the prefrontal cortex and dopamine release in the nucleus accumbens and …

SM Korte, J Prins, FS Van den Bergh… - European journal of …, 2017 - Elsevier
Abstract The 5-HT 1A/1B-receptor agonist eltoprazine has a behavioral drug signature that
resembles that of a variety of psychostimulant drugs, despite the differences in receptor …

Relationship between two forms of impulsivity in mice at baseline and under acute and sub-chronic atomoxetine treatment

M Kyriakidou, M Caballero-Puntiverio… - Progress in Neuro …, 2023 - Elsevier
Rationale Impulsivity is a symptom of various mental disorders, including attention deficit
hyperactivity disorder (ADHD), bipolar disorder, and addiction. Impulsivity is not a unitary …

Chronic atomoxetine treatment during adolescence decreases impulsive choice, but not impulsive action, in adult rats and alters markers of synaptic plasticity in the …

HS Sun, PJ Cocker, FD Zeeb, CA Winstanley - Psychopharmacology, 2012 - Springer
Rationale Impulsivity is a key symptom of attention-deficit hyperactivity disorder (ADHD). The
use of the norepinephrine reuptake inhibitor, atomoxetine, to treat ADHD suggests that the …