Similar to other diseases, genetic and environmental factors play important roles not only for
the development of osteoporosis but also for how individuals respond to drug treatment. The …

Bone is a major organ in the skeletal system that supports and protects muscles and other
organs, facilitates movement and hematopoiesis, and forms a reservoir of minerals including …

The explosive growth in the field of molecular biology over the last two decades has started
to make a great impact on clinical medicine. Genes have been cloned for diseases that were …

The genetic study of osteoporosis is one of the most important areas in bone and mineral
research. At this year's ASBMR Annual Meeting, great efforts were made in genome-wide …

Osteoporosis is a complicated and preventable disease with major morbidity complications
that affects millions of people. In the last 15 years, there have been numerous studies and …

Osteoporosis is a disease characterized by a deterioration of bone mass, architecture and
quality leading to a decreased bone strength and increased risk for fragility fractures …

Research has recently begun to clarify the genes and genetic variants that predispose to
osteoporosis and regulation of bone mass. Clinical applications of this research include the …

Every year, osteoporosis causes millions of fractures world-wide, with the lifetime risk of
suffering a wrist, hip, or vertebral fracture estimated to be about 30% in developed …

Research during the past several decades has unequivocally established a role of heredity
in the etiology of osteoporosis. Major efforts are currently underway to identify the genes and …

Osteoporosis causes more than 8.9 million fractures annually worldwide with the lifetime risk
for a wrist, hip, or vertebral fracture estimated to be in the order of 30–40% in developed …