The worldwide trend toward an aging population has resulted in a higher incidence of
chronic conditions, such as osteoporosis. Osteoporosis, a prevalent skeletal disorder …

Osteoporosis is a common disease with a strong genetic component characterized by
reduced bone mass and increased risk of fragility fractures. Twin and family studies have …

Epigenetics are such heritable modifications as DNA methylation, histone modification,
chromatin remodeling, as well as miRNA, without changes in DNA sequence. It has been …

Fractures related to osteoporosis occur in about 150 000 people annually in the United
Kingdom and account for over£ 750m in healthcare costs. As the age of the population …

Network and pathway-based analyses of genes associated with... : Medicine Network and
pathway-based analyses of genes associated with osteoporosis : Medicine Log in or Register …

Osteoporosis is a systemic skeletal disease characterized by low bone mass and
microarchitectural deterioration of bone with increased susceptibility to fractures in focal …

The last few years have seen considerable advances in our understanding of the genetic
factors influencing osteoporosis, driven by a range of break-throughs. The seven papers …

During the last 40 years, understanding of bone biology and the pathogenesis of
osteoporosis, the most common and impactful bone disease of old age, has improved …

For more than a decade, Wnt signaling pathways have been the focus of intense research
activity in bone biology laboratories because of their importance in skeletal development …