A pilot randomized clinical trial of cryopreserved versus liquid‐stored platelet transfusion for bleeding in cardiac surgery: the cryopreserved versus liquid platelet‐New …

S McGuinness, R Charlewood, E Gilder… - Vox …, 2022 - Wiley Online Library
Abstract Background and Objectives Platelets for transfusion have a shelf‐life of 7 days,
limiting availability and leading to wastage. Cryopreservation at− 80° C extends shelf‐life to …

A randomized, controlled pilot clinical trial of cryopreserved platelets for perioperative surgical bleeding: the CLIP‐I trial (Editorial, p. 2759)

MC Reade, DC Marks, R Bellomo, R Deans… - …, 2019 - Wiley Online Library
BACKGROUND Cryopreservation extends platelet (PLT) shelf life from 5 to 7 days to 2 to 4
years. However, only 73 patients have been transfused cryopreserved PLTs in published …

A clinical trial of frozen platelets: rationale, protocol and pilot analysis plan

DC Marks, L Johnson, MC Reade - ISBT Science Series, 2018 - Wiley Online Library
Introduction Platelets have a short shelf life and may be discarded due to expiry. Smaller
Australian hospitals often cannot justify keeping platelet units on‐site. Cryopreserved …

Cryopreserved platelets compared with liquid-stored platelets for the treatment of surgical bleeding: protocol for two multicentre randomised controlled blinded non …

MC Reade, DC Marks, B Howe, S McGuinness… - BMJ open, 2022 - bmjopen.bmj.com
Introduction Cryopreservation at− 80° C in dimethylsulphoxide extends platelet shelf-life
from 7 days to 2 years. Only limited comparative trial data supports the safety and …

[PDF][PDF] Vox Sanguinis International Forum on platelet cryopreservation: summary

CS Cohn, LJ Dumont, M Lozano, DC Marks… - Vox …, 2017 - academia.edu
The demand for platelets continues to rise, outstripping supply worldwide. In higher-income
countries, cancer patients remain platelet transfusion dependent for extended periods …

Postoperative Transfusions after Administration of Delayed Cold-stored Platelets versus Room Temperature Platelets in Cardiac Surgery: A Retrospective Cohort …

AM Klompas, S Zec, AC Hanson, T Weister… - …, 2023 - pubs.asahq.org
Background Delayed cold storage of room temperature platelets may extend shelf life from 5
to 14 days. The study hypothesized that the use of delayed cold-stored platelets in cardiac …

A Pilot Trial of Platelets Stored Cold versus at Room Temperature for Complex Cardiothoracic Surgery

G Strandenes, J Sivertsen, CK Bjerkvig, TK Fosse… - …, 2020 - pubs.asahq.org
Background This pilot trial focused on feasibility and safety to provide preliminary data to
evaluate the hemostatic potential of cold-stored platelets (2° to 6° C) compared with …

Safety and efficacy of autologous platelet transfusion in cardiac surgery: comparison of cryopreservation, blood collection on the day before surgery, and blood …

M Yokomuro, K Ebine, K Shiroma, S Tamura… - Cryobiology, 1999 - Elsevier
In a group of 39 patients with ischemic heart and valvular disease (January 1997 to May
1998), three platelet collection methods were compared in terms of safety and effectiveness …

The design of an adaptive clinical trial to evaluate the efficacy of platelets stored at low temperature in surgical patients

E Krachey, K Viele, PC Spinella… - Journal of Trauma …, 2018 - journals.lww.com
BACKGROUND Storage of platelets at 4 C compared with 22 C may increase both
hemostatic activity and storage duration; however, the maximum duration of cold storage is …

Frozen platelets for rural Australia: the CLIP trial

MC Reade, DC Marks, L Johnson… - … and Intensive Care, 2013 - search.proquest.com
Commenting on our review of frozen blood products1 in the previous issue of Anaesthesia
and Intensive Care, Dr Rowe from Armidale in country NSW eloquently highlights the clinical …