Platelet concentrates are universally prepared with a standard method and stored for 5 days
at room temperature (20–24 C) in gentle agitation. Currently, there is a renewed interest in …

More than 100 years ago, Duke transfused whole blood to a patient with thrombocytopenia
to raise the platelet count and prevent bleeding. Since then, platelet transfusions have …

Whole blood is currently being reintroduced as a blood product to be used in massive
bleeding situations because it affords plasma, red cells and platelets in a balanced ratio and …

Importance Approximately 15% of patients undergoing cardiac surgery receive frozen
plasma (FP) for bleeding. Four-factor prothrombin complex concentrates (PCCs) have …

Background Platelet (PLT) concentrates can be cryopreserved in dimethyl sulfoxide (DMSO)
and stored at− 80° C for 2 years. These storage conditions improve availability in both rural …

Background Platelets are a key component of massive transfusion in treating actively
bleeding patients. While optimized for prophylactic transfusions, the effectiveness of the …

OBJECTIVE: The study objective was to determine the effects of implementing a blood
conservation algorithm on blood product use and outcomes in a community cardiac surgery …

Abstract Background The Netherlands Armed Forces have been successfully using deep-
frozen (− 80° C) thrombocyte concentrate (DTC) for the treatment of (massive) bleeding …

This review considers the various methods currently in use, or under investigation, for the
storage of platelets intended for use in the treatment of active hemorrhage. The current …

Background Transfusion of cold‐stored platelet concentrates (CS‐PCs) appears effective in
massively bleeding patients. However, few studies have evaluated their in vivo hemostatic …