Impact of sacubitril/valsartan compared with ramipril on cardiac structure and function after acute myocardial infarction: the PARADISE-MI echocardiographic substudy

AM Shah, B Claggett, N Prasad, G Li, M Volquez… - Circulation, 2022 - Am Heart Assoc
Background: Angiotensin-converting enzyme inhibitors attenuate left ventricular (LV)
enlargement after acute myocardial infarction (AMI). Preclinical data suggest similar benefits …

Rationale and design of a multi‐center, prospective randomized controlled trial on the effects of sacubitril–valsartan versus enalapril on left ventricular remodeling in …

K Diao, D Wang, Z Chen, X Wu, M Ma, Y Zhu… - Clinical …, 2021 - Wiley Online Library
Background Angiotensin receptor neprilysin inhibitor (ARNI) sacubitril‐valsartan has been
recommended as one of the first‐line therapies in heart failure with reduced ejection fraction …

Comparison of the efficacy and safety of sacubitril/valsartan versus ramipril in patients with ST-segment elevation myocardial infarction

A Rezq, M Saad, M El Nozahi - The American journal of cardiology, 2021 - Elsevier
The role of sacubitril and/or valsartan in patient with heart failure (HF) is established.
Whether sacubitril and/or valsartan plays a role in improving outcomes in patients after ST …

The effects of angiotensin receptor-neprilysin inhibition on major coronary events in patients with acute myocardial infarction: insights from the PARADISE-MI trial

R Mehran, PG Steg, MA Pfeffer, K Jering, B Claggett… - Circulation, 2022 - Am Heart Assoc
Background: In patients who survive an acute myocardial infarction (AMI), angiotensin-
converting enzyme inhibitors decrease the risk of subsequent major cardiovascular events …

The benefits of sacubitril–valsartan in patients with acute myocardial infarction: a systematic review and meta‐analysis

B Xiong, D Nie, J Qian, Y Yao, G Yang… - ESC heart …, 2021 - Wiley Online Library
Aims We aimed to investigate whether sacubitril–valsartan could further improve the
prognosis, cardiac function, and left ventricular (LV) remodelling in patients following acute …

[HTML][HTML] Angiotensin receptor–neprilysin inhibition in acute myocardial infarction

MA Pfeffer, B Claggett, EF Lewis… - … England Journal of …, 2021 - Mass Medical Soc
Background In patients with symptomatic heart failure, sacubitril–valsartan has been found
to reduce the risk of hospitalization and death from cardiovascular causes more effectively …

Effects of sacubitril/valsartan on ventricular remodeling in patents with left ventricular systolic dysfunction following acute anterior wall myocardial infarction

H Wang, X Fu - Coronary artery disease, 2021 - journals.lww.com
Objective The aim of this study was to investigate the effect of sacubitril/valsartan (Sal/Val)
on left ventricular (LV) remodeling in patients with LV systolic dysfunction following acute …

Effects of losartan and captopril on left ventricular systolic and diastolic function after acute myocardial infarction: results of the Optimal Trial in Myocardial Infarction …

JE Møller, U Dahlström, O Gøtzsche, A Lahiri… - American Heart …, 2004 - Elsevier
BACKGROUND: Angiotensin-converting enzyme inhibitors have been shown to attenuate
adverse remodeling after acute myocardial infarction (AMI), and the same has been …

Changes in ventricular size and function in patients treated with valsartan, captopril, or both after myocardial infarction

SD Solomon, H Skali, NS Anavekar, M Bourgoun… - Circulation, 2005 - Am Heart Assoc
Background—Angiotensin-converting enzyme (ACE) inhibitors have been shown to
attenuate left ventricular (LV) enlargement in association with reducing mortality after …

Sacubitril/valsartan averts adverse post-infarction ventricular remodeling and preserves systolic function in rabbits

J Torrado, C Cain, AG Mauro, F Romeo… - Journal of the American …, 2018 - jacc.org
Abstract Background: Sacubitril/valsartan (SAC/VAL) is approved by the US Food and Drug
Administration for heart failure with reduced ejection fraction (HFrEF). Objectives: This study …