Neuroprotective Activities of Spirulina platensis in the 6-OHDA Model of Parkinson's Disease Are Related to Its Anti-Inflammatory Effects

FAV Lima, IP Joventino, FP Joventino… - Neurochemical …, 2017 - Springer
Spirulina platensis (SPI) is a cyanobacterium, presenting anti-inflammatory and antioxidant
actions. Considering the importance of inflammation and oxidative stress in Parkinson's …

Spirulina maxima pretreatment partially protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity

G Chamorro, M Pérez-Albiter… - Nutritional …, 2006 - Taylor & Francis
Spirulina is an alga that has a high nutritional value and some of its biological activities are
attributed to the presence of antioxidants. Oxidative stress is involved in Parkinson's …

Neuroprotective effect of Spirulina fusiform and amantadine in the 6-OHDA induced Parkinsonism in rats

I Chattopadhyaya, S Gupta, A Mohammed… - … and Alternative Medicine, 2015 - Springer
Background Multi-factorial etiology exists in pathophysiology of neurodegenerative
diseases. The imbalance of anti-oxidant enzymes and dopamine level leads to …

Antioxidant effect of Spirulina (Arthrospira) maxima in a neurotoxic model caused by 6-OHDA in the rat striatum

JC Tobón-Velasco, V Palafox-Sánchez… - Journal of Neural …, 2013 - Springer
There is evidence to support that an impaired energy metabolism and the excessive
generation of reactive oxygen species (ROS) contribute to brain injury in neurodegenerative …

Protective effects of a polysaccharide from Spirulina platensis on dopaminergic neurons in an MPTP-induced Parkinson's disease model in C57BL/6J mice

F Zhang, J Lu, J Zhang, J Xie - Neural regeneration research, 2015 - journals.lww.com
The present study aimed to determine whether a polysaccharide obtained from Spirulina
platensis shows protective effects on dopaminergic neurons. A Parkinson's disease model …

Spirulina platensis protects neurons via suppression of glial activation and peripheral sensitization leading to restoration of motor function in collagen-induced …

N Patro, A Sharma, K Kariaya, I Patro - 2011 - nopr.niscpr.res.in
Spirulina platensis treatment (400 mg kg-1 for 25 days) effectively suppressed peripheral
sensitization via modulation of glial activation and improved motor coordination and …

A Spirulina-Enhanced diet provides neuroprotection in an α-synuclein model of Parkinson's disease

MM Pabon, JN Jernberg, J Morganti, J Contreras… - 2012 - journals.plos.org
Inflammation in the brain plays a major role in neurodegenerative diseases. In particular,
microglial cell activation is believed to be associated with the pathogenesis of …

Neuroprotective effect of Spirulina in cerebral ischemia–reperfusion injury in rats

S Thaakur, R Sravanthi - Journal of neural transmission, 2010 - Springer
Epidemiological studies indicate that the intake of Mediterranean-style diet is inversely
associated with risk of stroke, cardiovascular diseases, and cancer. Spirulina is widely used …

Pre- and Early Post-treatment With Arthrospira platensis (Spirulina) Extract Impedes Lipopolysaccharide-triggered Neuroinflammation in Microglia

A Piovan, J Battaglia, R Filippini… - Frontiers in …, 2021 - frontiersin.org
Background: Uncontrolled neuroinflammation and microglia activation lead to cellular and
tissue damage contributing to neurodegenerative and neurological disorders. Spirulina …

Beneficial effects of spirulina consumption on brain health

T Trotta, C Porro, A Cianciulli, MA Panaro - Nutrients, 2022 - mdpi.com
Spirulina is a microscopic, filamentous cyanobacterium that grows in alkaline water bodies.
It is extensively utilized as a nutraceutical food supplement all over the world due to its high …