[HTML][HTML] Predicting future community-level ocular Chlamydia trachomatis infection prevalence using serological, clinical, molecular, and geospatial data

C Tedijanto, S Aragie, Z Tadesse, M Haile… - PLoS neglected …, 2022 - journals.plos.org
Trachoma is an infectious disease characterized by repeated exposures to Chlamydia
trachomatis (Ct) that may ultimately lead to blindness. Efficient identification of communities …

Spatial clustering of high load ocular Chlamydia trachomatis infection in trachoma: a cross-sectional population-based study

A Last, S Burr, N Alexander… - Pathogens and …, 2017 - academic.oup.com
Chlamydia trachomatis (Ct) is the most common cause of bacterial sexually transmitted
infection and infectious cause of blindness (trachoma) worldwide. Understanding the spatial …

[HTML][HTML] Serological and PCR-based markers of ocular Chlamydia trachomatis transmission in northern Ghana after elimination of trachoma as a public health …

LG Senyonjo, O Debrah, DL Martin… - PLoS neglected …, 2018 - journals.plos.org
Background Validation of elimination of trachoma as a public health problem is based on
clinical indicators, using the WHO simplified grading system. Chlamydia trachomatis (Ct) …

[HTML][HTML] The natural history of trachoma infection and disease in a Gambian cohort with frequent follow-up

NC Grassly, ME Ward, S Ferris… - PLoS neglected …, 2008 - journals.plos.org
Background The natural history of ocular Chlamydia trachomatis infections in endemic
communities has not been well characterised and is an important determinant of the …

[HTML][HTML] Population-based analysis of ocular Chlamydia trachomatis in trachoma-endemic West African communities identifies genomic markers of disease severity

AR Last, H Pickering, C Roberts, F Coll, J Phelan… - Genome medicine, 2018 - Springer
Abstract Background Chlamydia trachomatis (Ct) is the most common infectious cause of
blindness and bacterial sexually transmitted infection worldwide. Ct strain-specific …

[HTML][HTML] Prevalence of ocular Chlamydia trachomatis infection in Amhara region, Ethiopia, after 8 years of trachoma control interventions

SD Nash, A Chernet, P Weiss, AW Nute… - The American Journal …, 2023 - ncbi.nlm.nih.gov
Although trachoma mass drug administration (MDA) programs target ocular Chlamydia
trachomatis, the global trachoma control program does not monitor infection as a measure of …

The Epidemiology of Ocular Chlamydia trachomatis Infection within Districts Persistently Endemic for Trachoma in Amhara, Ethiopia

SD Nash, E Sata, A Chernet… - … journal of tropical …, 2024 - pubmed.ncbi.nlm.nih.gov
Persistent trachoma is a growing concern to trachoma control programs globally and
programs serving Ethiopia specifically. Persistent trachoma is defined as a district with two …

[HTML][HTML] The impact of a single round of community mass treatment with azithromycin on disease severity and ocular Chlamydia trachomatis load in treatment-naïve …

AR Last, SE Burr, E Harding-Esch, E Cassama… - Parasites & vectors, 2017 - Springer
Background Trachoma, a neglected tropical disease, is caused by ocular infection with
Chlamydia trachomatis (Ct). The World Health Organization (WHO) recommends three …

[HTML][HTML] The Distribution of Ocular Chlamydia Prevalence across Tanzanian Communities Where Trachoma Is Declining

SA Rahman, SK West, H Mkocha… - PLoS neglected …, 2015 - journals.plos.org
Background Mathematical models predict an exponential distribution of infection prevalence
across communities where a disease is disappearing. Trachoma control programs offer an …

[HTML][HTML] Estimating Household and Community Transmission of Ocular Chlamydia trachomatis

IM Blake, MJ Burton, RL Bailey… - PLoS neglected …, 2009 - journals.plos.org
Introduction Community-wide administration of antibiotics is one arm of a four-pronged
strategy in the global initiative to eliminate blindness due to trachoma. The potential impact …