Circulating microRNAs as noninvasive biomarkers in breast cancer

MA Cortez, JW Welsh, GA Calin - … disease and circulating tumor cells in …, 2012 - Springer
MicroRNAs (miRNAs) are master regulators of gene expression. By degrading or blocking
translation of messenger RNA targets, these non-coding RNAs can modulate the expression …

Roles of circulating microRNA (s) in human breast cancer

ZX Chong, SK Yeap, WY Ho - Archives of biochemistry and biophysics, 2020 - Elsevier
Abstract miRNAs are short non-coding RNA molecules that regulate the expression of
mRNA post-transcriptionally. MiRNAs that are secreted into the circulation, also termed …

The emerging role of microRNAs in breast cancer

Z Yang, Z Liu - Journal of Oncology, 2020 - Wiley Online Library
Breast cancer (BC) is the most common malignancy in women. Due to BC heterogeneity,
complexity, and metastasis, many BC patients do not successfully respond to therapies. The …

[HTML][HTML] Prognostic role of microRNAs in breast cancer: A systematic review

E Zografos, F Zagouri, D Kalapanida, R Zakopoulou… - Oncotarget, 2019 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) have been found to play an important role in breast cancer,
functioning either as potential oncogenes or tumor suppressor genes, but their role in the …

Dysregulation of microRNAs in breast cancer and their potential role as prognostic and predictive biomarkers in patient management

E van Schooneveld, H Wildiers, I Vergote… - Breast cancer …, 2015 - Springer
MicroRNAs (miRNAs) are an emerging class of gene expression modulators with relevant
roles in several biological processes, including cell differentiation, development, apoptosis …

microRNAs in breast cancer: regulatory roles governing the hallmarks of cancer

JN Goh, SY Loo, A Datta, KS Siveen… - Biological …, 2016 - Wiley Online Library
ABSTRACT A large number of etiological factors and the complexity of breast cancers
present challenges for prevention and treatment. Recently, the emergence of microRNAs …

[HTML][HTML] miRNA biomarkers in breast cancer detection and management

SW Fu, L Chen, Y Man - Journal of Cancer, 2011 - ncbi.nlm.nih.gov
Breast cancer is considered as a heterogeneous disease comprising various types of
neoplasms, which involves different profile changes in both mRNA and micro-RNA (miRNA) …

[HTML][HTML] Circulating microRNA-based screening tool for breast cancer

P Frères, S Wenric, M Boukerroucha, C Fasquelle… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Circulating microRNAs (miRNAs) are increasingly recognized as powerful biomarkers in
several pathologies, including breast cancer. Here, their plasmatic levels were measured to …

Circulating micro-RNAs as potential blood-based markers for early stage breast cancer detection

MG Schrauder, R Strick, R Schulz-Wendtland… - PloS one, 2012 - journals.plos.org
Introduction MicroRNAs (miRNAs, miRs) are a class of small, non-coding RNA molecules
with relevance as regulators of gene expression thereby affecting crucial processes in …

[HTML][HTML] MicroRNAs in pathogenesis of breast cancer: Implications in diagnosis and treatment

NR Shah, H Chen - World journal of clinical oncology, 2014 - ncbi.nlm.nih.gov
MicroRNAs (miRNAs) are small non-coding RNAs generated by a two-step complex process
and are post transcriptional negative regulators of their target mRNAs. Dysregulation of …