Abstract As per the World Health Organization, cancer is the second leading cause of death
globally and is responsible for an estimated 9.6 million deaths in 2018. More than 2 million …

Paclitaxel (PTX), a taxane plant product, is one of the most effective broad-spectrum anti-
cancer agents and approved for the treatment of a variety of cancers including ovarian …

Purpose Paclitaxel is an effective chemotherapeutic agent against a variety of cancer types.
However, the clinical utility of paclitaxel is restricted by its poor solubility in water and high …

Paclitaxel is one of the most widely used and effective antineoplastic agents derived from
natural sources. It has a wide spectrum of antitumor activity, particularly against ovarian …

Paclitaxel is one of the most effective chemotherapeutic drugs ever developed and is active
against a broad range of cancers, such as lung, ovarian, and breast cancers. Due to its low …

Introduction: Paclitaxel (PTX) is one of the most effective broad-spectrum chemotherapeutic
agents in the treatment of cancers. However, its clinical application has been limited due to …

Paclitaxel (PTX) is a potent anticancer agent whose clinical usefulness is marred by a
delivery problem that is caused by its unfavorable pharmacokinetic and physical properties …

Paclitaxel (PTX) is an effective anticancer chemical with a broad spectrum that was primarily
obtained from a curative shrub, specifically the bark of Taxus brevifolia tree. It belongs to a …

The main challenge encountered while treating using Paclitaxel (PTX) is its poor solubility in
aqueous solutions. The cremophor used in the formulation can cause various side effects …

Paclitaxel is a diterpenoid isolated from Taxus brevifolia. It is effective for various cancers,
especially ovarian and breast cancer. Due to its aqueous insolubility, it is administered …