Molecular mechanism of the anti-inflammatory effects of Sophorae Flavescentis Aiton identified by network pharmacology

N Zhu, J Hou - Scientific reports, 2021 - nature.com
Inflammation, a protective response against infection and injury, involves a variety of
biological processes. Sophorae Flavescentis (Kushen) is a promising Traditional Chinese …

Bioactive Compounds and Signaling Pathways of Wolfiporia extensa in Suppressing Inflammatory Response by Network Pharmacology

J Jin, MHU Chowdhury, M Hafizur Rahman, KY Choi… - Life, 2023 - mdpi.com
Wolfiporia extensa (WE) is a medicinal mushroom and an excellent source of naturally
occurring anti-inflammatory substances. However, the particular bioactive compound (s) and …

Dihydrosanguinarine based RNA-seq approach couple with network pharmacology attenuates LPS-induced inflammation through TNF/IL-17/PI3K/AKT pathways in …

Y Xiang, H Zhang, ZX Zhang, XY Qu, FX Zhu - International …, 2022 - Elsevier
Dihydrosanguinarine (DS) is one of the main chemical constituents of Corydalis bungeana
Turcz. which demonstrates anti-inflammatory, antioxidant, and antimicrobial in vitro. The …

Network pharmacology-based identifcation of potential targets of the flower of Trollius chinensis Bunge acting on anti-inflammatory effectss

J Liang, M Wang, KM Olounfeh, N Zhao, S Wang… - Scientific Reports, 2019 - nature.com
The flower of Trollius chinensis Bunge was widely used for the treatment of inflammation-
related diseases in traditional Chinese medicine (TCM). In order to clarify the anti …

Network pharmacology integrated with experimental validation revealed the anti-inflammatory effects of Andrographis paniculata

N Zhu, J Hou, N Yang - Scientific Reports, 2021 - nature.com
Inflammation is a key factor in the development and complications of various diseases
because it has a complex pathogenesis. Andrographis paniculate (Burm. f.) Nees (Chuan …

Isolation and identification of the components in Cybister chinensis Motschulsky against inflammation and their mechanisms of action based on network pharmacology …

YH Che, ZR Xu, LL Ni, XX Dong, ZZ Yang… - Journal of …, 2022 - Elsevier
Ethnopharmacological relevance Cybister chinensis Motschulsky belongs to the family
Dytiscidae. As a traditional Chinese medicine, the insect is called Longshi in the folk and is …

Investigation on the mechanism of 2, 3, 4′, 5-Tetrahydroxystilbene 2-oD-glucoside in the treatment of inflammation based on network pharmacology

L Sun, B Wang, T Sun, F Zhou, B Zhu, C Li… - Computers in biology …, 2022 - Elsevier
Background Inflammation is the pathogenesis of various chronic diseases plaguing clinic for
years. Fallopia multiflora (Thunb.) is a traditional Chinese herbal medicine with a long …

Network Pharmacology‐Based Identification of Potential Targets of Lonicerae japonicae Flos Acting on Anti‐Inflammatory Effects

X Guo, X Yu, B Zheng, L Zhang, F Zhang… - BioMed research …, 2021 - Wiley Online Library
Lonicerae japonicae flos (LJF) is widely used for the treatment of inflammation‐related
diseases in traditional Chinese medicine (TCM). To clarify the anti‐inflammatory mechanism …

Unravelling the anti-inflammatory mechanism of Allium cepa: an integration of network pharmacology and molecular docking approaches

V Omoboyede, OS Onile, BF Oyeyemi, RT Aruleba… - Molecular Diversity, 2023 - Springer
Allium cepa, commonly known as onion, is a widely consumed spice that possesses
numerous pharmacological properties. A. cepa bioactive components are often explored in …

A network pharmacology approach to investigate the anti-inflammatory mechanism of effective ingredients from Salvia miltiorrhiza

S Cui, S Chen, Q Wu, T Chen, S Li - International immunopharmacology, 2020 - Elsevier
Salvia miltiorrhiza, known as Danshen in Chinese, has been widely used to treat
cardiovascular diseases in China. Tanshinone I (Tan I) and cryptotanshinone (CST) are the …