Study on the multitarget mechanism of sanmiao pill on gouty arthritis based on network pharmacology

H Qian, Q Jin, Y Liu, N Wang, Y Chu… - Evidence‐Based …, 2020 - Wiley Online Library
Sanmiao pill (SMP), a Chinese traditional formula, had been used to treat gouty arthritis
(GA). However, the active compounds and underlying mechanism remained unclear. Hence …

Therapeutic effects of Siegesbeckia orientalis L. And its active compound luteolin in rheumatoid arthritis: Network pharmacology, molecular docking and experimental …

B Xiao, J Li, Z Qiao, S Yang, HY Kwan, T Jiang… - Journal of …, 2023 - Elsevier
Ethnopharmacological relevance Rheumatoid arthritis (RA) is a common difficult disease
with a high disability rate. Siegesbeckia orientalis L.(SO), a Chinese medicinal herb that is …

Dissecting and Evaluating the Therapeutic Targets of Coptis Chinensis Franch in the Treatment of Urinary Tract Infections Induced by Escherichia coli

Z Chang, J Zhang, M Lei, Z Jiang, X Wu… - Frontiers in …, 2022 - frontiersin.org
Coptis chinensis Franch (CCF) is extensively used in the treatment of inflammatory-related
diseases. Accumulating studies have previously demonstrated the anti-inflammatory …

Pharmacological basis of the use of the root bark of Zizyphus nummularia Aubrev. (Rhamnaceae) as anti-inflammatory agent

SD Ray, S Ray, M Zia-Ul-Haq, V De Feo… - … and Alternative Medicine, 2015 - Springer
Background The root bark of Zizyphus nummularia (Rhamnaceae) is traditionally used as an
anti-inflammatory agent. The current study aimed to explore the anti-inflammatory activity (in …

Construction of a “Bacteria-Metabolites” Co-Expression Network to Clarify the Anti–Ulcerative Colitis Effect of Flavonoids of Sophora flavescens Aiton by Regulating …

J Shao, Z Li, Y Gao, K Zhao, M Lin, Y Li… - Frontiers in …, 2021 - frontiersin.org
Ulcerative colitis (UC) is considered an immune disease, which is related to the dysbiosis of
intestinal microbiota and disorders of the host immune system and metabolism. Sophora …

Sophoraflavanone G from Sophora alopecuroides inhibits lipopolysaccharide-induced inflammation in RAW264. 7 cells by targeting PI3K/Akt, JAK/STAT and Nrf2/HO …

C Guo, L Yang, J Luo, C Zhang, Y Xia, T Ma… - International …, 2016 - Elsevier
Sophoraflavanone G (SG), a prenylated flavonoid from Sophora alopecuroides, has been
reported to have many pharmacological activities including anti-inflammation. However, the …

[HTML][HTML] Saponins from Aesculus wilsonii seeds exert anti-inflammatory activity through the suppression of NF-κB and NLRP3 pathway

H Li, H Cao, J Ruan, Y Wu, D Yang, Q Gao… - Arabian Journal of …, 2023 - Elsevier
The seeds of Aesculus wilsonii were reported to be rich in saponins and have anti-
inflammatory activity. However, the phytochemistry investigation of its saponins is not clear …

Integrated strategy of LC-MS and network pharmacology for predicting active constituents and pharmacological mechanisms of Ranunculus japonicus Thunb. for …

ZY Wang, FH Chu, NN Gu, Y Wang, D Feng… - Journal of …, 2021 - Elsevier
Abstract Ethnopharmacological relevance Ranunculus japonicus Thunb.(short for R.
japonicus) is a topically applied herb with the activities of removing jaundice, nebula and …

An investigation of the mechanism of rapid relief of ulcerative colitis induced by five-flavor Sophora flavescens enteric-coated capsules based on network …

S Gu, Y Xue, Y Zhang, K Chen, S Xue… - … Chemistry & High …, 2020 - ingentaconnect.com
Aim and Objective: Five-Flavor Sophora flavescens Enteric-Coated Capsules (FSEC) are
the only proprietary Chinese medicine approved for the treatment of ulcerative colitis (UC) in …

Discovery of Phenolic Glycoside from Hyssopus cuspidatus Attenuates LPS-Induced Inflammatory Responses by Inhibition of iNOS and COX-2 Expression through …

X Liu, J Su, G Wang, L Zheng, G Wang, Y Sun… - International Journal of …, 2021 - mdpi.com
It seems quite necessary to obtain effective substances from natural products against
inflammatory response (IR) as there are presently clinical problems regarding …