Biofilms and biocompatibility: discovering alternative targets for preventing biomaterial-associated infections

A Forson - 2022 - research.rug.nl
Medical implants are increasingly being utilised to either restore function after injury or
disease. This has presented two main challenges that threaten long-term implant …

[HTML][HTML] Micrococcal Nuclease stimulates Staphylococcus aureus Biofilm Formation in a Murine Implant Infection Model

AM Forson, CWK Rosman, TG van Kooten… - Frontiers in Cellular …, 2022 - frontiersin.org
Advancements in contemporary medicine have led to an increasing life expectancy which
has broadened the application of biomaterial implants. As each implant procedure has an …

[PDF][PDF] Micrococcal nuclease is essential for Staphylococcus aureus biofilm formation in a murine implant infection model

AM Forson, CWK Rosman, TG Van Kooten… - … aureus nuclease: a …, 2022 - research.rug.nl
Advancements in contemporary medicine have led to an increasing life expectancy, which
has broadened the application of biomaterial implants. As each implant procedure has an …

Multifunctional coatings and nanotopographies: toward cell instructive and antibacterial implants

C Mas‐Moruno, B Su, MJ Dalby - Advanced healthcare …, 2019 - Wiley Online Library
In biomaterials science, it is nowadays well accepted that improving the biointegration of
dental and orthopedic implants with surrounding tissues is a major goal. However, implant …

Innate immune response in implant-associated infections: neutrophils against biofilms

U Dapunt, GM Hänsch, CR Arciola - Materials, 2016 - mdpi.com
Biofilm has been recognized as a well-protected form of living for bacteria, contributing to
bacterial pathogenicity, particularly for opportunistic species. Biofilm-associated infections …

Biofilms associated with biomedical implants and combating therapies

HP Nagaiah, K Kandaswamy, A Priya, T Kasthuri… - Understanding Microbial …, 2023 - Elsevier
Biofilms are created by microscopic organisms such as bacteria and fungi, which are the
communal cause of chronic infections in nosocomial and medical-device-related …

[PDF][PDF] The biotolerability and in vivo efficacy of an antifouling pNIPMAM-based nanogel coating in preventing surgical mesh associated infections

AM Forson, D Keskin, TG van Kooten… - … alternative targets for …, 2022 - research.rug.nl
Biomaterials pose as a substantial risk for bacterial infections. Infections are serious adverse
events when associated with implanted biomaterials such as surgical meshes, where …

Tuning surface topographies on biomaterials to control bacterial infection

S Khalid, A Gao, G Wang, PK Chu, H Wang - Biomaterials Science, 2020 - pubs.rsc.org
Microbial contamination and subsequent formation of biofilms frequently cause failure of
surgical implants and a good understanding of the bacteria–surface interactions is vital to …

Transforming medical device biofilm control with surface treatment using microfabrication techniques

MT Al Bataineh, A Alazzam - Plos one, 2023 - journals.plos.org
Biofilm deposition on indwelling medical devices and implanted biomaterials is frequently
attributed to the prevalence of resistant infections in humans. Further, the nature of persistent …

Nanometric considerations in biofilm formation

JS Fernandez-Moure, A Mydlowska, C Shin… - Surgical …, 2019 - liebertpub.com
Prosthetic contamination and biofilm formation continue to plague implanted materials. With
increasing resistance to traditional antibiotic regimens, alternative approaches to preventing …