Nanotopography Influences Host–Pathogen Quorum Sensing and Facilitates Selection of Bioactive Metabolites in Mesenchymal Stromal Cells and Pseudomonas …

R Cuahtecontzi Delint, MI Ishak… - … Applied Materials & …, 2024 - ACS Publications
Orthopedic implant-related bacterial infections and resultant antibiotic-resistant biofilms
hinder implant–tissue integration and failure. Biofilm quorum sensing (QS) communication …

[HTML][HTML] Material-based treatment strategies against intraosseous implant biofilm infection

Z Pan, C Dai, W Li - Biochemistry and Biophysics Reports, 2024 - Elsevier
Implant-associated infections present a significant clinical obstacle for orthopedic
practitioners, with bacterial biofilm formation serving as a pivotal factor in the initiation …

Functionalized biomaterials to combat biofilms

D Huang, J Wang, K Ren, J Ji - Biomaterials Science, 2020 - pubs.rsc.org
Pathogenic microbial biofilms that readily form on implantable medical devices or human
tissues have posed a great threat to worldwide healthcare. Hopes are focused on preventive …

How microbes read the map: Effects of implant topography on bacterial adhesion and biofilm formation

SW Lee, KS Phillips, H Gu, M Kazemzadeh-Narbat… - Biomaterials, 2021 - Elsevier
Microbes have remarkable capabilities to attach to the surface of implanted medical devices
and form biofilms that adversely impact device function and increase the risk of multidrug …

Surface texturing and combinatorial approaches to improve biocompatibility of implanted biomaterials

LC Xu, CA Siedlecki - Frontiers in physics, 2022 - frontiersin.org
Biomaterial associated microbial infection and blood thrombosis are two of the barriers that
inhibit the successful use of implantable medical devices in modern healthcare. Modification …

Assessment of the biofilm-forming ability on solid surfaces of periprosthetic infection-associated pathogens

JA Cho, YJ Roh, HR Son, H Choi, JW Lee, SJ Kim… - Scientific Reports, 2022 - nature.com
Biofilm formation is one of the leading causes of complications after surgery in clinical
settings. In this study, we profiled the biofilm-forming ability of various periprosthetic infection …

Perspectives on biomaterial-associated infection: pathogenesis and current clinical demands

D Bai, J Chen, P Li, W Huang - Racing for the Surface: Pathogenesis of …, 2020 - Springer
In this chapter, an overview of current medical implant devices and infection problems
associated with implantation is provided, bridging the gap between material engineering …

Impact of solid surface hydrophobicity and micrococcal nuclease production on Staphylococcus aureus Newman biofilms

AM Forson, HC van der Mei, J Sjollema - Scientific Reports, 2020 - nature.com
Staphylococcus aureus is commonly associated with biofilm-related infections and
contributes to the large financial loss that accompany nosocomial infections. The …

Mechanism of cell integration on biomaterial implant surfaces in the presence of bacterial contamination

C Yue, HC van der Mei, R Kuijer… - … Research Part A, 2015 - Wiley Online Library
Bacterial contamination during biomaterial implantation is often unavoidable, yielding a
combat between cells and bacteria. Here we aim to determine the modulatory function of …

Characterization of inflammatory and fibrotic encapsulation responses of implanted materials with bacterial infection

NA Rohner, GD Learn, MJ Wiggins… - ACS Biomaterials …, 2021 - ACS Publications
Medical device infections are costly, while preclinical assessment of antimicrobial properties
for new materials is time intensive and imperfect at capturing the interrelated aspects of …