[HTML][HTML] Local tissue interactions across the dorsal midline of the forebrain establish CNS laterality
The mechanisms that establish behavioral, cognitive, and neuroanatomical asymmetries are
poorly understood. In this study, we analyze the events that regulate development of …
poorly understood. In this study, we analyze the events that regulate development of …
[HTML][HTML] A nodal signaling pathway regulates the laterality of neuroanatomical asymmetries in the zebrafish forebrain
Animals show behavioral asymmetries that are mediated by differences between the left and
right sides of the brain. We report that the laterality of asymmetric development of the …
right sides of the brain. We report that the laterality of asymmetric development of the …
[HTML][HTML] Brain asymmetry is encoded at the level of axon terminal morphology
Background Functional lateralization is a conserved feature of the central nervous system
(CNS). However, underlying left-right asymmetries within neural circuitry and the …
(CNS). However, underlying left-right asymmetries within neural circuitry and the …
[HTML][HTML] Ontogenesis of lateralization
O Güntürkün, S Ocklenburg - Neuron, 2017 - cell.com
The brains of humans and other animals are asymmetrically organized, but we still know
little about the ontogenetic and neural fundaments of lateralizations. Here, we review the …
little about the ontogenetic and neural fundaments of lateralizations. Here, we review the …
Nodal signalling imposes left-right asymmetry upon neurogenesis in the habenular nuclei
The habenulae are evolutionarily conserved bilateral nuclei in the epithalamus that relay
input from the forebrain to the ventral midbrain. In zebrafish, the habenulae display left-right …
input from the forebrain to the ventral midbrain. In zebrafish, the habenulae display left-right …
[HTML][HTML] Six3 represses nodal activity to establish early brain asymmetry in zebrafish
A Inbal, SH Kim, J Shin, L Solnica-Krezel - Neuron, 2007 - cell.com
The vertebrate brain is anatomically and functionally asymmetric; however, the molecular
mechanisms that establish left-right brain patterning are largely unknown. In zebrafish …
mechanisms that establish left-right brain patterning are largely unknown. In zebrafish …
Selective asymmetry in a conserved forebrain to midbrain projection
YS Kuan, JT Gamse, AM Schreiber… - … Zoology Part B …, 2007 - Wiley Online Library
How the left and right sides of the brain acquire anatomical and functional specializations is
not well understood. The zebrafish has proven to be a useful model to explore the genetic …
not well understood. The zebrafish has proven to be a useful model to explore the genetic …
Leaning to the left: laterality in the zebrafish forebrain
How the brain becomes lateralized is poorly understood. By contrast, much is known about
molecular cues that specify the left–right axis of the body, fashioning the asymmetric …
molecular cues that specify the left–right axis of the body, fashioning the asymmetric …
[HTML][HTML] Wnt/Axin1/β-catenin signaling regulates asymmetric nodal activation, elaboration, and concordance of CNS asymmetries
Nodal activity in the left lateral plate mesoderm (LPM) is required to activate left-sided Nodal
signaling in the epithalamic region of the zebrafish forebrain. Epithalamic Nodal signaling …
signaling in the epithalamic region of the zebrafish forebrain. Epithalamic Nodal signaling …
[HTML][HTML] Brain lateralization: a comparative perspective
O Güntürkün, F Ströckens… - Physiological …, 2020 - journals.physiology.org
Comparative studies on brain asymmetry date back to the 19th century but then largely
disappeared due to the assumption that lateralization is uniquely human. Since the …
disappeared due to the assumption that lateralization is uniquely human. Since the …